现代医药卫生2025，Vol.41Issue(6)：1334-1337,4.DOI:10.3969/j.issn.1009-5519.2025.06.010
13种婴幼儿及儿童呼吸道感染病原体特征分析
Analysis of pathogen characteristics of 13 respiratory infections in infants and children
摘要
Abstract
Objective To investigate the composition and epidemic characteristics of 13 pathogens cau-sing respiratory infections n infants,children and other infants in Guigang area,and to provide effective assis-tance for the prevention,control,diagnosis and treatment of clinical pathogen infections.Methods A total of 1 889 cases of children with fever,cough,fatigue and other symptoms who came to the hospital from January to July 2024 were collected.Thirteen respiratory pathogens[including HRV,HRSV,InfB,HMPV,HADV,MP,InfA,etc.]were detected by multiplex real-time fluorescent quantitative reverse transcription polymerase chain reaction and capillary electrophoresis,and statistical analysis was performed.Results Among the 1 889 samples,1 562 cases(82.69%)were positive for respiratory pathogens,including 1 147 cases(73.43%)of sin-gle infection and 415 cases(26.57%)of multiple infection.Among multiple infections,368 cases(23.56%)were double infection,43 cases(2.75%)were triple infection,and 4 cases(0.26%)were quadruple infection.The main respiratory pathogens in single infection were HRV[29.73%(341/1 147)],HRSV[24.24%(278/1 147)],followed by InfB[8.89%(102/1 147)],HMPV[6.71%(77/1 147)],HADV[6.45%(74/1 147)]etc.The mixed infection of multiple respiratory pathogens was mainly double infection,and the top three were HRV+HADV(13.04%),HRV+HRSV(11.14%),HRV+MP(9.24%).The comparison of pathogen infec-tion rates(excluding quadruple infections)among children of different age groups showed statistically signifi-cant differences(P<0.05).The single infection rate of children in the early childhood period was higher than that of children in the infancy period,and the double infection rate of children in the early childhood and pre-school period was higher than that of children in the infancy period.The differences were statistically signifi-cant(P<0.05).In single infections,InfA in children of different age groups.In single infections,there were statistically significant differences in the infection rates of InfA,HADV,HPIV,InfB,MP,and HRSV among children of different age groups(P<0.05).Conclusion The epidemic characteristics of different respiratory pathogens vary in different periods of infants,toddlers and children.The main pathogens of respiratory tract infections in infants,young children and children are HRV and HRSV.Among them,the combinations of mul-tiple infection pathogens are mainly HRV+HADV,HRV+HRSV and HRV+MP.关键词
病原体/呼吸道感染/婴幼儿/儿童Key words
Pathogen/Respiratory tract infection/Infants/Children分类
医药卫生引用本文复制引用
李腾,郭静,黄菊,黄威祥..13种婴幼儿及儿童呼吸道感染病原体特征分析[J].现代医药卫生,2025,41(6):1334-1337,4.基金项目
贵港市科学技术局自筹经费科研项目(贵科攻2400014). （贵科攻2400014）
