现代医药卫生2025，Vol.41Issue(6)：1343-1347,5.DOI:10.3969/j.issn.1009-5519.2025.06.012
NIV治疗AECOPD合并Ⅱ型呼吸衰竭的临床研究
Clinical study of NIV in the treatment of AECOPD complicated with type Ⅱ respiratory failure
胡锦平 1郑振华 2华文娟 3张玉芳 2李少敏 2葛立波4
作者信息
- 1. 景德镇市第四人民医院老年科,江西 景德镇 333000
- 2. 华侨大学附属厦门长庚医院放疗科,福建 厦门 361028
- 3. 华侨大学附属厦门长庚医院心内科,福建 厦门 361028
- 4. 华侨大学附属厦门长庚医院呼吸与危重症医学科,福建 厦门 361028
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy of noninvasive mechanical ventilation(NIV)in the treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD)complicated with type Ⅱ respiratory failure.Methods A total of 94 patients with AECOPD complicated with type II respirato-ry failure admitted to the Fourth People's Hospital of Jingdezhen from June 2020 to October 2022 were select-ed and divided into the treatment group(46 cases)and the control group(48 cases)according to whether non-invasive ventilators were used.The clinical efficacy,partial pressure of oxygen(PaO2),partial pressure of car-bon dioxide(PaCO2),blood oxygen saturation(SpO2),pH value,heart rate,respiratory rate and incidence of complications were compared between the two groups.Results The total effective rate of the treatment group(100.00%)was higher than that of the control group(43.75%),and the difference was statistically significant(P<0.05).After treatment,there were statistically significant differences in SPO2,PaO2,PaCO2,heart rate,respiratory rate and pH value between the two groups(P<0.05).There was significant difference in the inci-dence of complications between the two groups(P<0.05).There was no significant difference in hospitaliza-tion time and antibiotic use time between the two groups(P>0.05).The use of noninvasive ventilator had a strong positive impact on the clinical efficacy,but the result was not statistically significant(P>0.05).Con-clusion The use of NIV in the treatment of AECOPD complicated with type II respiratory failure can im-prove the clinical efficacy,enhance respiratory function and reduce the incidence of complications.关键词
慢性阻塞性肺疾病/无创机械通气/呼吸衰竭/临床疗效Key words
Chronic obstructive pulmonary disease/Noninvasive mechanical ventilation/Respirato-ry failure/Clinical efficacy分类
医药卫生引用本文复制引用
胡锦平,郑振华,华文娟,张玉芳,李少敏,葛立波..NIV治疗AECOPD合并Ⅱ型呼吸衰竭的临床研究[J].现代医药卫生,2025,41(6):1343-1347,5.
