现代医药卫生2025，Vol.41Issue(6)：1475-1479,5.DOI:10.3969/j.issn.1009-5519.2025.06.038
肠肺轴在慢性阻塞性肺疾病急性加重期中的免疫调控机制
Immune regulation mechanism of enteropulmonary axis in acute exacerbation of chronic obstructive pulmonary disease
摘要
Abstract
Chronic obstructive pulmonary disease(COPD)is a common disease characterized by persis-tent airway inflammation and airflow restriction.In recent years,the immune regulation function of enteropul-monary axis in acute exacerbation of COPD(AECOPD)has attracted extensive attention.The imbalance of in-testinal microbiota,the destruction of mucosal barrier function and systemic inflammatory response may ag-gravate lung inflammation and accelerate the progress of disease through complex immune mechanisms.This article reviews the immune regulation mechanism of enteropulmonary axis in AECOPD,aiming to provide new ideas and strategies for the prevention and treatment of AECOPD.关键词
肠肺轴/慢性阻塞性肺疾病/急性加重期/免疫机制/综述Key words
Pulmonary axis/Chronic obstructive pulmonary disease/Acute exacerbation/Im-mune mechanism/Review分类
医药卫生引用本文复制引用
罗明生,万东..肠肺轴在慢性阻塞性肺疾病急性加重期中的免疫调控机制[J].现代医药卫生,2025,41(6):1475-1479,5.基金项目
重庆市科学技术委员会项目(cstc2018jcyjAX0158). （cstc2018jcyjAX0158）
