新医学2025，Vol.56Issue(6)：543-552,10.DOI:10.12464/j.issn.0253-9802.2025-0164
多学科诊疗联合减重代谢手术模式在肥胖合并终末期肾病患者中的应用
Application of multi-disciplinary diagnosis and treatment integrated metabolic and bariatric surgery in patients with obesity and end-stage kidney disease
摘要
Abstract
Obesity is an independent risk factor for end-stage kidney disease(ESKD),significantly increasing treatment difficulty and leading to worsened prognosis.Metabolic and bariatric surgery effectively addresses obesity in ESKD patients by reducing body weight,improving metabolic disorders,slowing renal function decline,and increasing kidney transplant success rates.However,these patients face higher surgical risks,necessitating individualized assessment and optimized perioperative management through a multidisciplinary team(MDT)approach,including nutritional support,complication prevention,and long-term follow-up.This article explores the mechanisms,clinical benefits,and perioperative management strategies of metabolic and bariatric surgery through a literature review and two case reports.While MDT and this surgical approach represents a promising therapeutic strategy for obese ESKD patients,its broader clinical implementation requires further high-quality evidence for validation.关键词
肥胖症/终末期肾病/减重代谢手术/多学科Key words
Obesity/ESKD/Metabolic and bariatric surgery/Multidisciplinary引用本文复制引用
雷普润,谭莺,杨奕,陈图锋,朱延华,陈燕铭..多学科诊疗联合减重代谢手术模式在肥胖合并终末期肾病患者中的应用[J].新医学,2025,56(6):543-552,10.基金项目
国家自然科学基金(82270886) （82270886）
中山大学临床医学研究5010计划(2023006) （2023006）
