中国病理生理杂志2025，Vol.41Issue(6)：1242-1248,7.DOI:10.3969/j.issn.1000-4718.2025.06.023
脑灌注导向的重症患者血压管理的研究进展
Advances in cerebral perfusion-guided blood pressure management in critically ill patients
摘要
Abstract
Abnormal cerebral perfusion impacts not only short-term brain function but may also cause irrevers-ible neurological deficits,significantly affecting patient prognosis.In intensive care units(ICU),patients often exhibit he-modynamic instability,intracranial pathologies,and impaired cerebrovascular autoregulation,which may result in cere-bral perfusion disorders,particularly cerebral hypoperfusion.Cerebral perfusion is determined by three key factors:blood pressure,intracranial pressure,and cerebrovascular regulatory function.Given that ICU patients have various types of un-derlying primary diseases,there is a need for unified standards regarding optimal blood pressure maintenance for all pa-tients and specific patient categories.Furthermore,cerebral perfusion-oriented blood pressure management requires indi-vidualized approaches for each patient.Therefore,the monitoring and integration of these parameters during ICU diagnos-tic and therapeutic processes are particularly crucial.关键词
重症患者/血压管理/脑灌注Key words
critically ill patients/blood pressure management/cerebral perfusion分类
临床医学引用本文复制引用
方乐平,陈博,李俊杰,汪志刚..脑灌注导向的重症患者血压管理的研究进展[J].中国病理生理杂志,2025,41(6):1242-1248,7.基金项目
广州市科技局市校(院)企联合资助专题(No.2023A03J0592) （院）
