中国比较医学杂志2025，Vol.35Issue(5)：155-163,9.DOI:10.3969/j.issn.1671-7856.2025.05.015
咽喉反流性疾病动物模型和相关评价指标的研究进展
Research progress in animal models and related evaluation indexes of laryngopharyngeal reflux disease
摘要
Abstract
Laryngopharyngeal reflux disease(LPRD)occurs in the upper respiratory tract and the upper digestive tract.Its pathogenesis is complex and there a lack of effective treatments.Suitable animal models and standard evaluation method are needed to explore the pathogenesis of this disease and to develop new therapeutic drugs.New Zealand rabbits are commonly used to model LPRD,via balloon dilatation.The standard evaluation method for LPRD include symptom observation and evaluation,imaging evaluation,and pH monitoring.This review considers the animal models and evaluation indexes currently used for pharyngeal reflux with reference to the global literature,to provide a reference for future research.关键词
咽喉反流性疾病/动物/模型/指标评价/进展Key words
laryngopharyngeal reflux disease/animals/model/index evaluation/progress引用本文复制引用
韦秀红,甄甄,张俊波,马艳苗,李贤煜..咽喉反流性疾病动物模型和相关评价指标的研究进展[J].中国比较医学杂志,2025,35(5):155-163,9.基金项目
中药复杂作用解析协同创新团队项目(XTCX2023001). （XTCX2023001）
