中国医学装备2025，Vol.22Issue(6)：45-49,5.DOI:10.3969/j.issn.1672-8270.2025.06.009
对比剂双期双流法在陈旧性心肌梗死患者心脏磁共振"一站式"检查流程的应用研究
Application of contrast agent dual-phase double-flow method in CMR"one-stop"examination process of patients with old myocardial infarction
摘要
Abstract
Objective:To explore the influence of injection methods of different contrast agents on CMR image quality,and further optimize"one-stop"examination process under the premise of the analysis for high-pressure bolus pressure curve of contrast-enhanced(CE)cardiac magnetic resonance(CMR).Methods:The data of CMR examination of 70 patients with old myocardial infarction who admitted to the department of emergency of Xuanwu Hospital,Capital Medical University from December 2023 to December 2024 were selected as research objects.They were divided into an observation group and a control group by a simple randomization method,with 35 cases in each group.The observation group adopted gadolinium contrast agent injection with double-phase double-flow,with two bolus injections at 4 ml/s and 2 ml/s sequentially.The control group adopted the injection with single-phase double-flow,with only one bolus injection at 4 ml/s.The dynamic pressure time curve was drawn,and the total bolus dose and pressure peak of two kinds of injection methods were compared.The residual liquid samples of the observation group and the control group were collected after injection of contrast agent was conducted.After the residual liquids of 10 ml,20 ml and 30 ml were derived respectively,the T1 mapping sequence was used to collect signal intensity values,and to compared the difference of that between two groups.The signal-to-noise ratio(SNR)of left ventricular blood pool,infarcted myocardium and distal myocardium,and the contrast-to-noise ratios(CNR)between infarcted myocardium and blood pool,and between distal myocardium and blood pool were compared between the observation group and the control group.Results:There was no statistical difference in the total dose of bolus injection between the observation group and the control group(P>0.05).The peak value of the pressure of bolus injection in the observation group and control group were respectively(87.4±11.3)pound force per square inch(PSI)and(104.0±20.1)PSI,and the difference was statistically significant(t=5.81,P<0.05).T1 signal intensity values of 10 ml residual liquid and 20 mL residual liquid were respectively 1984.43±70.26 and 2190.56±195.96 in observation group,and they were respectively 1203.36±184.99 and 2884.64±349.39 in control group,and the differences were significant(t=-3.57,6.03,P<0.05).The T1 signal intensity value of 30mL residual fluid sample was 4371.75±75.16 in observation group,and that was 4261.86±110.68 in control group,and the difference was no significant(P>0.05).The SNR value of blood pool was(4.88±1.01)in observation group,which was lower than(8.25±1.36)in control group,and the difference of that between two groups was significant(t=6.11,P<0.05).The CNR values of infarcted myocardium and blood pool,of remote myocardium and blood pool between two groups were statistically significant(t=-4.79,-5.39,P<0.05).Conclusion:The contrast agent of high-pressure bolus injection with dual-phase dual-flow method can not only explore the time window of the extravasation of contrast agent,but also improve the SNR and the CNR of CMR images,and further optimize the CMR examination process.关键词
双期双流/心脏磁共振(CMR)/钆对比剂/信噪比(SNR)/对比噪声比(CNR)Key words
Dual-phase double-flow/Cardiac magnetic resonance(CMR)/Gadolinium contrast agent/Signal-to-noise ratio(SNR)/Contrast to noise ratio(CNR)分类
临床医学引用本文复制引用
李爽,孙峥,赵丽,刘志,王梓迪,霍光研,卢洁..对比剂双期双流法在陈旧性心肌梗死患者心脏磁共振"一站式"检查流程的应用研究[J].中国医学装备,2025,22(6):45-49,5.基金项目
国家自然科学基金面上项目(62172288) （62172288）
首都医科大学本科学生科研创新项目(XSKY2024396) （XSKY2024396）
首都医科大学宣武医院临床研究课题(LCYJ202410) The National Natural Science Foundation of China(62172288) （LCYJ202410）
Capital Medical University Undergraduate Innovation Project(XSKY2024396) （XSKY2024396）
Xuanwu Hospital of Capital Medical University Clinical research Project(LCYJ202410) （LCYJ202410）
