中国中医药信息杂志2025，Vol.32Issue(7)：192-196,5.DOI:10.19879/j.cnki.1005-5304.202405541
中药复方干预抽动障碍实验研究进展
Experimental Research Progress in TCM Compounds for the Prevention and Treatment of Tic Disorders
摘要
Abstract
Tic disorder is a chronic neuropsychiatric disorder with complex etiology and diverse phenotypes,and its incidence has been increasing significantly in recent years.Most scholars believe that abnormalities in the cortico-striatal-thalamo-cortical circuit and its interconnected brain regions are closely related to the development of tic disorder.Chinese materia medica intervention in tic disorders is characterized by multi-targets,multi-mechanisms and holistic nature,and has a good prospect for research application.This article summarized the experimental studies of TCM compound intervention in tic disorder in recent years,which have shown that TCM compounds could reduce the damage of nerve cells through the regulation of neurotransmitters,inflammatory response,immune function and the"colony-gut-brain axis"to improve and prevent tic disorder,which could provide a reference for the research and development of new medicines for tic disorder and for the clinical research.关键词
抽动障碍/多发性抽动症/中药复方/作用机制/综述Key words
tic disorder/Tourette syndrome/TCM compound/mechanism/review分类
医药卫生引用本文复制引用
钟佳霖,张茂福,高旅,冯鹏,尚菁,史正刚..中药复方干预抽动障碍实验研究进展[J].中国中医药信息杂志,2025,32(7):192-196,5.基金项目
国家自然科学基金(82305318) （82305318）
甘肃省自然科学基金(22JR11RG221) （22JR11RG221）
中国中药协会儿童健康与药物研究专业委员会资助项目(ENQNJJ-2023-01) （ENQNJJ-2023-01）
山西省中医药管理局项目(2022ZYYC257) （2022ZYYC257）
甘肃省高校青年博士支持项目(2023QB-075) （2023QB-075）
