中国医学装备2025，Vol.22Issue(6)：76-80,5.DOI:10.3969/j.issn.1672-8270.2025.06.015
电子支气管镜对临床活动期气管支气管结核介入治疗的疗效研究
Discussion on curative effect of electronic bronchoscope in treating tracheobronchial tuberculosis at clinical activity stage
摘要
Abstract
Objective:To evaluate the clinically curative effect of intervention treatment of electronic bronchoscope in treating tracheobronchial tuberculosis at clinical activity stage.Methods:Sixty patients with tracheobronchial tuberculosis at clinical activity stage(type I,II,III and VI)who admitted to Liuzhou People's Hospital from September 2020 to September 2023 were selected,and they were divided into drug group(anti-tuberculosis drug treatment)and combination group(anti-tuberculosis drug treatment+interventional treatment with electronic bronchoscope)by the random number table method,with 30 cases in each group.The curative effects of the two groups were observed,and the negative conversion rate of sputum bacteria,clinical symptom scores(cough symptom,expectoration symptom)before and after treatment,Modified British Medical Research Council Dyspnea Scale(mMRC)score between two groups were compared,and the differences in indicators of pulmonary function such as forced expiratory volume in the first second(FEV1),forced vital capacity(FVC)and maximum voluntary ventilation(MVV)between the two groups also were compared.And then,the incidence of complications was calculated.Results:During the 1,2 and 3 months of follow-up,there were respectively 21 cases,27 cases and 30 cases occurred negative conversion of sputum bacteria in 30 patients of the combination group,and there were respectively 15 cases,18 cases and 23 cases occurred negative conversion of sputum bacteria in 30 patients of the drug group.At the 1st month of follow-up,the negative conversion rate of sputum bacteria in combination group was higher than that in drug group,while there was no statistically significant difference between the two groups(P＞0.05).At the 2nd and 3rd month of follow-up,the negative conversion rate of sputum bacteria in the combination group was higher than that in the drug group,and the differences were statistically significant(x2=7.200,7.925,P<0.05).The effective rate of treatment of the combination group was 100%,which was higher than 80%of the drug group,and the difference of that between two groups was significant(x2=6.667,P<0.05).After 2 months of treatment,the mMRC score,cough symptom score and expectoration symptom score of the combination group were all lower than those of the drug group,and the differences were statistically significant(t=3.504,3.950,3.530,P<0.05).The improvement effects of FEV1,FVC and MVV of the combination group were all better than those of the drug group,and the differences were statistically significant(t=6.626,4.966,4.097,P<0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusion:Anti-tuberculosis drug therapy combined with electronic bronchoscopy intervention has a good therapeutic effect in clinically active tracheobronchial tuberculosis.关键词
气管支气管结核/临床活动期/电子支气管镜/介入治疗Key words
Tracheobronchial tuberculosis/Clinical activity stage/Electronic bronchoscope/Interventional treatment分类
医药卫生引用本文复制引用
莫胜林,孔晋亮,蒋忠胜,黄云,黄小红,唐贵,孙艳萍,覃锦玉,陈涛,胡家光,张鹏..电子支气管镜对临床活动期气管支气管结核介入治疗的疗效研究[J].中国医学装备,2025,22(6):76-80,5.基金项目
广西医药卫生科研课题(Z-B20221309,Z-B20221305,Z-B20221375) Medical and Health Research Projects in Guangxi(Z-B20221309,Z-B20221305,Z-B20221375) （Z-B20221309,Z-B20221305,Z-B20221375）
