中国输血杂志2025，Vol.38Issue(6)：828-832,5.DOI:10.13303/j.cjbt.issn.1004-549x.2025.06.013
三种红细胞成分血储存期末溶血率的5年回顾性研究
Hemolysis rates of three red blood cell components at the end of storage:a 5-year retrospective study
摘要
Abstract
Objective To evaluate the suitability of the existing hemolysis rate standards for locally processed red blood cell components by retrospectively analyzing 5-year hemolysis rate data at the end of storage.Methods A total of 720 blood samples of three types of red blood cell components from our blood station from January 2019 to December 2023 were collect-ed.Parameters included hemoglobin concentration(Hb),hematocrit(Hct),and free hemoglobin concentration(fHb).Hemolysis rate were taken as the control standard of 0.8%in accordance with the national standard.The hemolysis rates were compared against the national standard threshold of 0.8%(GB18469-2012),and annual trends of the detection pa-rameters were observed.Results The hemolysis rates(±s,%)of leukocyte-depleted whole blood at the end of storage were(0.038±0.023 8)in 2019,(0.049±0.039 5)in 2020,(0.043±0.040 7)in 2021,(0.049±0.030 7)in 2022,and(0.058±0.054 8)in 2023,respectively;The hemolysis rates(±s,%)of leukocyte-depleted suspended red blood cells at the end of storage were(0.093±0.050 2)in 2019,(0.086±0.049 5)in 2020,(0.123±0.072 3)in 2021,(0.122±0.052 1)in 2022,and(0.106±0.058 6)in 2023,respectively;The hemolysis rates(±s,%)of washed red blood cells at the end of storage were(0.127±0.038 2)in 2019,(0.150±0.066 5)in 2020,(0.121±0.052 2)in 2021,(0.124±0.038 9)in 2022,and(0.128±0.044 3)in 2023,respectively.Conclusion Hemolysis rates at the end of blood storage of three red blood cell components were significantly lower than the limits specified in Quality Requirements for Whole Blood and Components(GB18469-2012),as well as standards from the EU,AABB and the United States.The results demonstrate excellent product quality control.A regional internal control standard of<0.2%is proposed for hemolysis rates at the end of storage.关键词
红细胞成分血/储存期末溶血率/质量标准Key words
red blood cell components/hemolysis rate at the end of storage/quality standard分类
医药卫生引用本文复制引用
卢珍萍,刘福发,康美艳,吴宪彬,王燕婷,龙星,邱新璐,李津..三种红细胞成分血储存期末溶血率的5年回顾性研究[J].中国输血杂志,2025,38(6):828-832,5.基金项目
2023年赣州市科技计划项目(GZ2023ZSF430) （GZ2023ZSF430）
