中国现代中药2025，Vol.27Issue(6)：1190-1196,7.DOI:10.13313/j.issn.1673-4890.20241028010
中药气雾剂/喷雾剂治疗心绞痛的临床应用进展
Clinical Application Progress of Traditional Chinese Medicine Aerosols/Sprays in Treatment of Angina Pectoris
摘要
Abstract
Angina pectoris is caused by acute myocardial ischemia and hypoxia due to inadequate coronary blood supply.If not treated in a timely manner,it may progress to life-threatening myocardial infarction.Traditional Chinese medicine(TCM)aerosols can effectively alleviate the clinical symptoms such as chest tightness and chest pain of patients with angina pectoris during an attack,offering advantages including fewer adverse reactions and rapid onset of action via sublingual or pulmonary administration.Leveraging interdisciplinary research achievements in pharmacology,pharmaceutics,and natural product chemistry,this review systematically introduced the preparation techniques,formulation characteristics,and the advantages of sublingual and pulmonary routes for drug absorption.Subsequently,the applications of five TCM aerosols/sprays in the treatment of angina pectoris were reviewed in the context of TCM syndrome differentiation and the principles of precise medication.As a novel dosage form,TCM aerosols accelerate drug onset while preserving the fundamental therapeutic effects or indications of the herbs.Given the multi-syndrome characteristics of angina pectoris,effective treatment requires both combination therapy targeting distinct mechanisms and the development of syndrome-specific aerosol products.关键词
心绞痛/中药气雾剂/中药喷雾剂/舌下喷药/肺部吸入/中药新剂型研发Key words
angina pectoris/traditional Chinese medicine aerosol/traditional Chinese medicine spray/sublingual administration/pulmonary inhalation/development of novel TCM dosage form分类
中医学引用本文复制引用
卢卫娅,张斯杰,余战锋,徐晖,杨旭,魏振平,何红涛..中药气雾剂/喷雾剂治疗心绞痛的临床应用进展[J].中国现代中药,2025,27(6):1190-1196,7.基金项目
河北省中医药管理局科研计划项目(2020299) （2020299）
河北省政府资助临床医学优秀人才培养项目(13000022P00DE34100247) （13000022P00DE34100247）
