中国中医药信息杂志2025，Vol.32Issue(7)：67-72,6.DOI:10.19879/j.cnki.1005-5304.202407054
中医药治疗银屑病临床试验注册现状分析
Analysis of the Current Status of Clinical Trial Registration for TCM in the Treatment of Psoriasis
摘要
Abstract
Objective To analyze the clinical trial projects of TCM treatment for psoriasis registered at the China Clinical Trial Registry(ChiCTR);To provide references for clinical research in this field.Methods Clinical trial studies on the TCM treatment for psoriasis were retrieved from the ChiCTR database from the establishment of the database to June 17,2024.Excel 2019 and GraphPad Prism 9.0 were used to organize and analyze the general characteristics included in registered clinical trials.Results Totally 65 TCM-related trials were included,of which 58(89.23%)were prospectively registered,and 55(84.62%)had undergone ethical review.The majority of trials were registered in Guangdong,Beijing and Shanghai,collectively accounting for 78.46%(n=51)of the total.The leading institution,Guangdong Provincial Hospital of Chinese Medicine,contributed 19 trials.Funding was predominantly sourced from governmental bodies,with 72.31%(n=47)supported by national or regional grants.Among the registered studies,interventional trials predominated(n=56),including 46 randomised parallel-controlled designs.Blinding was implemented in 23 trials,and biospecimen collection was reported in 48 studies.40 trials were single-centre studies,and a cumulative sample size was 17 695 participants.Common interventions included oral administration of classical TCM formulations or hospital-prepared remedies,alongside topical applications such as medicated baths and ointments.The primary outcome measure in most trials was the Psoriasis Area and Severity Index.Conclusion While the number of registered clinical trials on TCM for psoriasis in China demonstrates a fluctuating yet upward trend,the overall volume remains modest.Disparities in regional distribution,methodological variability,and incomplete trial registration details highlight areas for improvement.关键词
银屑病/临床试验/中国临床试验注册中心/中医药Key words
psoriasis/clinical trials/Chinese Clinical Trial Registry/TCM分类
医药卫生引用本文复制引用
杨忆衡,张展,梁彪,钱诗维,倪嘉淳,黄硕,韩昌鹏,王振宜..中医药治疗银屑病临床试验注册现状分析[J].中国中医药信息杂志,2025,32(7):67-72,6.基金项目
国家自然科学基金面上项目(82274531、81973859、82174393) （82274531、81973859、82174393）
上海市卫生健康委员会卫生行业临床研究专项面上项目(202140185) （202140185）
