中国现代中药2025，Vol.27Issue(6)：1099-1105,7.DOI:10.13313/j.issn.1673-4890.20240725009
基于质量评价和抗炎活性的石菖蒲干燥方法筛选
Screening of Drying Methods for Acorus tatarinowii Schott Based on Quality and Anti-inflammatory Activity Evaluation
摘要
Abstract
Objective:To evaluate the effects of different drying methods on the quality and anti-inflammatory activity of Acorus tatarinowii.Methods:Fresh samples of A.tatarinowii were sun-dried,shade-dried,freeze-dried,far-infrared dried,and blast-dried at 50,60,70,and 90℃.The heavy metals,moisture,total ash,leachate,volatile oil,and drying rate of A.tatarinowii samples dried with different methods were assessed.The Coomassie brilliant blue method was employed to determine the protein content.The lipopolysaccharide-induced inflammation model was established with RAW264.7 cells,and the Griess reagent method was adopted to measure the nitric oxide release from the cells.The anti-inflammatory activities of A.tatarinowii samples dried with different methods were evaluated based on the levels of tumor necrosis factor-α,interleukin-6,reactive oxygen species,lactate dehydrogenase,and catalase,which were determined by detection kit.The effects of different drying methods on the quality of A.tatarinowii were evaluated by entropy weight-TOPSIS method using the quality indexes and anti-inflammatory activity A.tatarinowii herbs as evaluation indexes.Results:The comprehensive performance of different drying methods for A.tatarinowii followed the trend of blast drying at 70℃>blast drying at 60℃>freeze drying>blast drying at 50℃>shade drying>far-infrared drying>sun drying>blast drying at 90℃.Conclusion:The best drying method for A.tatarinowii is blast drying at 70℃.关键词
石菖蒲/熵权-优劣解距离法/干燥/质量/抗炎活性Key words
Acorus tatarinowii Schott/entropy weight TOPSIS/drying/quality/anti-inflammatory activity分类
医药卫生引用本文复制引用
米霄玉,伍蕙岚,陈琦,高楚倩,张琳玉,张路,胡运海,曾建国,谢红旗..基于质量评价和抗炎活性的石菖蒲干燥方法筛选[J].中国现代中药,2025,27(6):1099-1105,7.基金项目
湖南省中药材产业技术体系专项(HARS) （HARS）
财政部和农业农村部:国家现代农业产业技术体系资助项目 （）
