首页|期刊导航|International Journal of Oral Science|Dimethyl fumarate modulates M1/M2 macrophage polarization to ameliorate periodontal destruction by increasing TUFM-mediated mitophagy

Dimethyl fumarate modulates M1/M2 macrophage polarization to ameliorate periodontal destruction by increasing TUFM-mediated mitophagy

Liang Chen Pengxiao Hu Xinhua Hong Bin Li Yifan Ping Shuomin Chen Tianle Jiang Haofu Jiang Yixin Mao Yang Chen Zhongchen Song Zhou Ye Xiaoyu Sun Shufan Zhao Shengbin Huang

International Journal of Oral Science2025，Vol.17Issue(3)：P.434-447,14.

International Journal of Oral Science2025，Vol.17Issue(3)：P.434-447,14.DOI:10.1038/s41368-025-00360-0

Dimethyl fumarate modulates M1/M2 macrophage polarization to ameliorate periodontal destruction by increasing TUFM-mediated mitophagy

Liang Chen ¹Pengxiao Hu ¹Xinhua Hong ¹Bin Li ¹Yifan Ping ¹Shuomin Chen ¹Tianle Jiang ¹Haofu Jiang ¹Yixin Mao ²Yang Chen ²Zhongchen Song ³Zhou Ye ⁴Xiaoyu Sun ⁵Shufan Zhao ⁶Shengbin Huang²

作者信息

1. Institute of Stomatology,School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,China
2. Institute of Stomatology,School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,China Department of Prosthodontics,School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,China
3. Department of Periodontology,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,China College of Stomatology,Shanghai Jiao Tong University,Shanghai,China National Center for Stomatology,National Clinical Research Center for Oral Diseases,Shanghai Key Laboratory of Stomatology,Shanghai,China
4. Applied Oral Sciences and Community Dental Care,Faculty of Dentistry,University of Hong Kong,Hong Kong,China
5. Institute of Stomatology,School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,China Department of Periodontology,School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,China
6. Institute of Stomatology,School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,China Department of Oral Maxillofacial Surgery,School and Hospital of Stomatology,Wenzhou Medical University,Wenzhou,China
折叠

摘要

关键词

mitophagy/TUFM/inhibited periodontal destructionenhanced/alveolar bone resorption/dimethyl fumarate/oral disease/periodontal tissuesdimethyl fumarate dmf/periodontitis

分类

医药卫生

引用本文复制引用

Liang Chen,Pengxiao Hu,Xinhua Hong,Bin Li,Yifan Ping,Shuomin Chen,Tianle Jiang,Haofu Jiang,Yixin Mao,Yang Chen,Zhongchen Song,Zhou Ye,Xiaoyu Sun,Shufan Zhao,Shengbin Huang..Dimethyl fumarate modulates M1/M2 macrophage polarization to ameliorate periodontal destruction by increasing TUFM-mediated mitophagy[J].International Journal of Oral Science,2025,17(3):P.434-447,14.

基金项目

supported by the following grants:Natural Science Foundation of China(grant nos.82270991) （grant nos.82270991）

Zhejiang Provincial Natural Science Foundation of China/Outstanding Youth Science Foundation(grant no.LR21H140002) （grant no.LR21H140002）

Medical Health Science and Technology Major Project of Zhejiang Provincial Health Commission(grant no.WKJ-ZJ-2311) （grant no.WKJ-ZJ-2311）

Wenzhou Science and Technology Bureau Public Welfare Social Development(Medical and Health)Science and Technology Project(grant no.ZY2021015) （Medical and Health）

Opening Research Fund from Shanghai Key Laboratory of Stomatology,Shanghai Ninth People’s Hospital,College of Stomatology,Shanghai Jiao Tong University School of Medicine(grant no.2022SKLS-KFKT011) （grant no.2022SKLS-KFKT011）

Guangxi Key Laboratory of the Rehabilitation and Reconstruction for Oral and Maxillofacial Research(grant no.GXKLRROM2106) （grant no.GXKLRROM2106）

State Key Laboratory of Oral Diseases Open Fund(grant no.SKLOD2024OF08). （grant no.SKLOD2024OF08）

International Journal of Oral Science

ISSN：1674-2818

访问量0

下载量0

段落导航