分析测试学报2025，Vol.44Issue(7)：1313-1320,8.DOI:10.12452/j.fxcsxb.241112522
基于UiO-66-NH2金属有机框架复合MWCNTs电化学传感器构建及吗啡检测
Construction of an Electrochemical Sensor Based on UiO-66-NH2 Metal-Organic Framework Composite with MWCNTs for Morphine Detection
摘要
Abstract
Porous metal-organic framework materials(UiO-66-NH2)were prepared using hydrother-mal and composite materials of UiO-66-NH2/multi-walled carbon nanotubes(MWCNTs)were formed using ultrasonic mechanical mixing method.An electrochemical sensor was constructed using the drop-coating method.The composition and morphological structure of the materials were analyzed us-ing X-ray diffraction,field emission scanning electron microscopy,field emission transmission elec-tron microscope and Fourier-transform infrared spectroscopy.The electrochemical performance of the modified electrode was investigated using cyclic voltammetry with potassium ferricyanide as the elec-tron probe,and the electrochemical response of the electrode to morphine was examined using pulse voltammetry.The detection conditions,such as the mass ratio of the modified materials,enrichment time,and pH were optimized.The constructed sensor exhibited a high electrochemical response to morphine,with a linear detection range of 10-100 μmol/L and a minimum detection limit(S/N=3)of 9.922 μmol/L.The sensor demonstrated good stability,repeatability(RSD=4.1%),and anti-inter-ference ability(RSD<5.0%).The standard addition method was used to detect morphine in sweat and urine samples with recoveries of 92.1%-98.4%and RSD(n=3)below 5.0%.关键词
毒品/吗啡/电化学/传感器/金属有机框架Key words
illicit drugs/morphine/electrochemistry/sensors/metal-organic frameworks分类
化学化工引用本文复制引用
任书芳,刘亚慧,曹莉,王子涵,陈雨,刘迪..基于UiO-66-NH2金属有机框架复合MWCNTs电化学传感器构建及吗啡检测[J].分析测试学报,2025,44(7):1313-1320,8.基金项目
国家自然科学基金地区项目(22164003) （22164003）
甘肃政法大学校级科研创新项目(GZF2024XZDA02) （GZF2024XZDA02）
甘肃省科技计划项目(23JRRA1228) （23JRRA1228）
甘肃省自然科学基金实验动物专项项目(22JR5RA597) （22JR5RA597）
