分析化学2025，Vol.53Issue(6)：853-863,11.DOI:10.19756/j.issn.0253-3820.241348
基于表面增强拉曼光谱检测常见毒品的研究进展
Advances in Detection of Common Drugs Based on Surface Enhanced Raman Spectroscopy
摘要
Abstract
The number and types of drug abuse are increasing all over the world.The detection of drug suspects and biological samples of drug users plays an important role in forensic medicine.Surface-enhanced Raman spectroscopy(SERS)has the characteristics of fingerprint recognition,high sensitivity,high accuracy,fast and nondestructive,and is not interfered by water molecules.SERS has been widely used in detection of trace drugs and drugs in complex matrices.This paper introduced the types of SERS substrates applied to drug detection and the development status of portable SERS instruments.The research progresses of SERS in drug detection in the past five years were reviewed,focusing on the types of SERS detected drugs,the design of enhanced substrates,detection methods and detection limits.Finally,the application prospect of SERS technology in drug detection was discussed to provide reference for the development of drug detection technology in the future.关键词
表面增强拉曼光谱/复杂基质/毒品检测/评述Key words
Surface-enhanced Raman spectroscopy/Complex matrix/Illicit drug detection/Review引用本文复制引用
吕建华,陈俊秋,吕长利..基于表面增强拉曼光谱检测常见毒品的研究进展[J].分析化学,2025,53(6):853-863,11.基金项目
云南省科技计划项目-基础研究专项-青年项目(No.202101AU0023)、云南警官学院校级科研项目重点课题项目(No.21A022)、国家自然科学基金项目(No.82260337)和云南警官学院校级科研项目(No.21A015)资助. Supported by the Yunnan Province Science and Technology Project(No.202101AU0023),the Scientific Research Fund of Yunnan Police College for 2021(No.21A022),the National Natural Science Foundation of China(No.82260337)and the Scientific Research Fund of Yunnan Police College(No.21A015). （No.202101AU0023）
