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穿戴式动态黄疸水平及生理参数监测系统设计

黄婷 庄启瑶 杨茂帅 黄伟家 邹佐凤 熊涛 毛红 杨刚

集成电路与嵌入式系统2025,Vol.25Issue(7):28-35,8.
集成电路与嵌入式系统2025,Vol.25Issue(7):28-35,8.DOI:10.20193/j.ices2097-4191.2025.0015

穿戴式动态黄疸水平及生理参数监测系统设计

Design of wearable dynamic jaundice level and physiological parameter monitoring system

黄婷 1庄启瑶 1杨茂帅 1黄伟家 1邹佐凤 1熊涛 2毛红 3杨刚1

作者信息

  • 1. 四川大学生物医学工程学院医学信息及仪器系,成都 610065
  • 2. 四川大学华西第二医院儿科,成都 610041
  • 3. 四川省中医药科学院中医研究所肛肠科,成都 610031
  • 折叠

摘要

Abstract

Due to the high risk of neonatal jaundice and the limitations of traditional monitoring methods,a wearable dynamic jaundice level and physiological parameter monitoring system has been designed to meet the clinical demand for non-invasive dynamic jaundice de-tection equipment.The system includes a forehead-mounted wireless physiological signal collector,a Bluetooth communication host and a data analysis platform based on Lab VIEW.The system uses the highly integrated MAX86916 optical sensor to synchronously collect four-channel photoplethysmography(PPG)signals,and obtains bilirubin,heart rate,and blood oxygen saturation data through signal processing.The nRF52832 microcontroller with Bluetooth Low Energy(BLE)protocol is used for wireless communication.The data is transmitted wirelessly to the Bluetooth communication host,and then uploaded to the LabVIEW program of the PC via USB for display and storage.To verify the functionality and performance of the system,basic parameter tests,and comparative tests of each physiologi-cal parameter with commercial instruments were conducted in sequence.The device(13.5 g,41 mm×29.7 mm×15.1 mm)can con-tinuously monitor for 5 hours.The detection range of the bilirubin prediction model is 1~13 mg/dL.Measurements demonstrated bili-rubin,heart rate and blood oxygen are in strong agreement with standard instruments(p>0.05).And the maximum absolute errors for bilirubin,HR,and SpO2 measurements are 0.96 mg/dL,1 bpm,and 2.1%,respectively.Moreover,the system can sensitively track the decrease in heart rate after exercise and the variations in blood oxygen during breath-holding.The experiment results show that the system is effective in monitoring jaundice,heart rate and blood oxygen level.It features lightweight design,wearability,multi-para-metric detection,and non-invasive dynamic measurement capabilities.After further optimization,it is expected to be applied in neonatal clinical monitoring.

关键词

黄疸/MAX86916/多参数/无创监测/低功耗蓝牙

Key words

jaundice/MAX86916/multi-parameter/non-invasive monitoring/Bluetooth low energy

分类

信息技术与安全科学

引用本文复制引用

黄婷,庄启瑶,杨茂帅,黄伟家,邹佐凤,熊涛,毛红,杨刚..穿戴式动态黄疸水平及生理参数监测系统设计[J].集成电路与嵌入式系统,2025,25(7):28-35,8.

基金项目

四川省科技计划项目(2024YFFK0044,2024YFFK0273) (2024YFFK0044,2024YFFK0273)

集成电路与嵌入式系统

1009-623X

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