广西医学2025，Vol.47Issue(5)：686-694,9.DOI:10.11675/j.issn.0253-4304.2025.05.08
胆道闭锁患儿肝门空肠吻合术后感染发生情况及其危险因素分析
Occurrence status of infection in children with biliary atresia after Kasai procedure and its risk factors:an analytic study
摘要
Abstract
Objective To explore the occurrence status of infection after Kasai procedure(KP)in children with biliary atresia and its risk factors.Methods A retrospective study was performed to analyze the clinical data of 397 children with biliary atresia receiving KP,and children were assigned to non-infection group(159 cases)or infection group(238 cases)according to the presence of infection occurrence after surgery.The subgroup analysis was performed on the infection group,and relevant clinical data were compared between the non-infection group and the infection group.The multivariate Logistic regression model was adopted to analyze the risk factors for children with biliary atresia suffering from infection after KP.Results The incidence rate of infection among 397 children with biliary atresia after KP was 59.9%(238/397),and the incidence rate of cholangitis was 57.2%(227/397).The preoperative body weight and gamma-glutamyl transpeptidase of the infection group was higher than those of the non-infection group,and the preoperative serum total bile acid level,preoperative body weight,and preoperative height of the early infection group were higher than those of the late infection group(P<0.05).The multivariate Logistic regression analysis revealed that high preoperative body weight,high preoperative total bilirubin,and low preoperative AST level were the risk factors for the occurrence of infection in children with biliary atresia after KP(P<0.05).Conclusion High preoperative body weight,high preoperative total bilirubin and low preoperative AST level are the risk factors for the occurrence of infection in children with biliary atresia after KP.关键词
胆道闭锁/术后/患儿/感染/胆管炎/肝功能/危险因素Key words
Biliary atresia/Postoperation/Children/Infection/Cholangitis/Liver function/Risk factors分类
医药卫生引用本文复制引用
蒙宣宇,梁淑恒,黄丽,唐清,云翔,单庆文,陈秀奇..胆道闭锁患儿肝门空肠吻合术后感染发生情况及其危险因素分析[J].广西医学,2025,47(5):686-694,9.基金项目
广西壮族自治区卫生健康委员会自筹经费科研课题(Z-A20220282) （Z-A20220282）
广西科技计划项目(桂科AD22035219) （桂科AD22035219）
