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A simplified and reproducible ex vivo model of cold and ischemia-reperfusion injury

Lele Zhang Mingjie Ding Ying Zhu Zhiping Yan Wenzhi Guo

肝脏研究(英文)2025,Vol.9Issue(2):178-185,8.
肝脏研究(英文)2025,Vol.9Issue(2):178-185,8.DOI:10.1016/j.livres.2025.04.005

A simplified and reproducible ex vivo model of cold and ischemia-reperfusion injury

A simplified and reproducible ex vivo model of cold and ischemia-reperfusion injury

Lele Zhang 1Mingjie Ding 1Ying Zhu 2Zhiping Yan 3Wenzhi Guo1

作者信息

  • 1. Department of Hepatobiliary and Pancreatic Surgery,The First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan,China||Henan Key Laboratory for Hepatopathy and Transplantation Medicine,Zhengzhou,Henan,China||Henan Key Laboratory of Digestive Organ Transplantation,The First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan,China
  • 2. Department of Hepatobiliary and Pancreatic Surgery,The First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan,China
  • 3. Henan Key Laboratory for Hepatopathy and Transplantation Medicine,Zhengzhou,Henan,China||Henan Key Laboratory of Digestive Organ Transplantation,The First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan,China
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摘要

关键词

Liver transplantation/Animal model/Ischemia-reperfusion injury/Static cold storage(SCS)/Normothermic machine perfusion(NMP)/Ex vivo rat model

Key words

Liver transplantation/Animal model/Ischemia-reperfusion injury/Static cold storage(SCS)/Normothermic machine perfusion(NMP)/Ex vivo rat model

引用本文复制引用

Lele Zhang,Mingjie Ding,Ying Zhu,Zhiping Yan,Wenzhi Guo..A simplified and reproducible ex vivo model of cold and ischemia-reperfusion injury[J].肝脏研究(英文),2025,9(2):178-185,8.

基金项目

This work was supported by the National Natural Science Foundation of China(No.82400773,82400745,82370646),Young Talent Support Program of Henan Association for Science and Technology(No.2025HYTP083).We acknowledge assistance with the access of analytic instruments from Henan Key Laboratory of Digestive Organ Transplantation and Translational Medical Center of The First Affiliated Hospital of Zhengzhou University.Graphic illustrations were created with BioRender.com. (No.82400773,82400745,82370646)

肝脏研究(英文)

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