家畜生态学报2025，Vol.46Issue(6)：29-35,7.DOI:10.3969/j.issn.1673-1182.2025.06.005
关中奶山羊产奶性状候选基因ALDH18A1和PRKAG1的生物信息学分析
Bioinformatics Analysis of Candidate Genes ALDH18A1 and PRKAG1 for Milk Production Traits in Guanzhong Dairy Goats
摘要
Abstract
In order to explore the structure and function of proteins encoded by candidate genes AL-DH18A1 and PRKAG1 for milk production traits in Guanzhong dairy goats,the selected signals of AL-DH18A1 and PRKAG1 genes on the genome were analyzed based on Fst,θπ and Tajima'D methods.The linkage disequilibrium analysis of the selected sites was carried out to identify the linkage situation of the sites.Finally,the structure of the gene encoded protein was determined by bioinformatics analysis,and the influence of non-synonymous mutations in the gene on the encoded protein was predicted,which laid a the-oretical foundation for molecular breeding of Guanzhong dairy goats.关键词
关中奶山羊/产奶性状/ALDH18A1/PRKAG1/非同义突变Key words
Guanzhong dairy goat/milk production traits/ALDH18A1/PRKAG1/nonsynonymous mutations分类
农业科技引用本文复制引用
杨利娜,王卫宁,倪洁,贤明,孟金铭,胡建宏..关中奶山羊产奶性状候选基因ALDH18A1和PRKAG1的生物信息学分析[J].家畜生态学报,2025,46(6):29-35,7.基金项目
陕西省重点研发计划项目(2020ZDLNY02-04) （2020ZDLNY02-04）
陕西省技术创新引导专项(2022QFY11-04) （2022QFY11-04）
