中国卫生事业管理2025，Vol.42Issue(6)：637-642,650,7.
抗高血压药实施国家集中带量采购政策效果分析
Analysis of the Effect of Implementation of National Centralized Drug Procurement Policy in China for Antihyper-tensive Drugs
摘要
Abstract
Objective To analyze the impact of the national centralized drug procurement(NCDP)policy on the sales volume,procurement amount and average daily cost of selected antihypertensive drugs,explore the implementation effect of the national centralized procurement of antihypertensive drugs,and put forward targeted policy recommendations to improve the antihypertens-ive drug centralized procurement.Methods The hospital procurement data of antihypertensive drugs selected in the 5th batch of centralized national drug procurement in the Pharnexcloud database from the 1st quarter of 2019 to the 4th quarter of 2023 were se-lected to analyze the effect of the implementation of centralized procurement of antihypertensive drugs by the interrupted series model.Results After the implementation of the national centralized procurement policy,the antihypertensive drug market has shown significant structural adjustment.The procurement volume of the selected variety of benazepril increased dramatically by 74,383.90 thousand DDDs(P＜0.01),while the non-selected variety decreased sharply by 49,962.29 thousand DDDs(P＜0.01).The market share of the original drug decreased significantly from about 70％before the policy to 34％.In terms of pro-curement amount,the amount of the selected variety increased by 419,455.2 thousand CNY(P＜0.01)due to the increase pro-curement volume,but the daily cost(DDDc)decreased significantly from 1.613 yuan to 1.007 yuan(β2=-0.606,P＜0.01),while the DDDc of the non-selected variety remained at 2.11 yuan(β0+β2=2.238-0.126).The procurement volume and procurement cost of the alternative drug ramipril also fluctuated,but the policy effect was weaker than that of the selected drug benazepril.Conclusion The NCDP policy effectively reduced drug expenses,improved accessibility,and shifted clinical prefer-ences toward cost-effective generics,while diminishing the dominance of originator drugs.These findings underscore the need to expand centralized procurement to more antihypertensive drugs,balancing clinical demand,patient affordability,and domestic production capacity to maximize the public health benefits.关键词
集中带量采购/抗高血压药/政策效果Key words
National Centralized Drug Procurement/antihypertensive drugs/policy effects分类
医药卫生引用本文复制引用
薛原,万家欢,穆耕林,杨晨唯..抗高血压药实施国家集中带量采购政策效果分析[J].中国卫生事业管理,2025,42(6):637-642,650,7.基金项目
江苏省"青蓝工程"优秀青年骨干教师资助项目(苏教师函[2023]27号) （苏教师函[2023]27号）
中国健康管理协会科研课题"新医改背景下临床集采用药真实世界信息研究框架构建课题"(中健协发[2024]125号) （中健协发[2024]125号）
南京大学中国医院改革发展研究院课题项目 （）
江苏省宁爱医学发展医疗救助基金项目"我国药品集中带量采购政策实施效果评价及其优化建议"(NDYG224014),江苏高校哲学社会科学研究项目"江苏省社会组织参与社区居家养老服务能力提升路径研究"(2021SJA2460) （NDYG224014）
