中国实验动物学报2025，Vol.33Issue(6)：866-877,12.DOI:10.3969/j.issn.1005-4847.2025.06.009
组学技术在疾病动物模型评价中的应用
Progress in evaluation of animal disease models based on omics technologies
摘要
Abstract
Animal disease models are important biological tools for basic medical research.Establishing an ideal animal model is a critical prerequisite for acquiring reliable experimental data.By enabling molecular-level characterization,omics technologies can enhance the precision of animal model assessments,thereby improving the evaluation criteria.This review summarizes the current applications of omics in evaluating animal disease models,discusses their potential for quality control implementation,and proposes novel frameworks for standardized model validation.关键词
组学技术/疾病动物模型/评价标准/质量控制/生物标志物Key words
omics technologies/animal disease model/evaluation standard/quality control/biomarkers分类
生物科学引用本文复制引用
朱超,郭星,王金娥,董平轩,高倩倩,王晓玥,戚晓杰,田金举..组学技术在疾病动物模型评价中的应用[J].中国实验动物学报,2025,33(6):866-877,12.基金项目
国家自然科学基金(32071392),山东省自然科学基金(ZR2024QH557),德州学院科研启动基金(2022xjrc420).Funded by National Natural Science Foundation of China(32071392),Shandong Province Natural Science Foundation(ZR2024QH557),Dezhou University Scientific Research Start-Up Foundation(2022xjrc420). （32071392）
