摘要
Abstract
Objective To identify main risk factors for secretory otitis media(SOM)in patients with adenoid hypertrophy(AH)for preventive strategies.Methods The Cochrane Library,PubMed,EMBASE,Web of Science,CNKI,VIP,WanFang Data and CBM were searched for studies on risk factors for recurrent SOM in patients with AH.From retrieved studies,pooled estimates were generated using the RevMan 5.4 software.Results A total of 11 studies were included,The pooled odds ratio(OR)was 4.50 for age(95%CI=4.03～5.01,P<0.01),0.60 for duration of disease(95%CI=0.47～0.78,P<0.01),1.45 for nasal congestion and rhinorrhea(95%CI=0.99～2.11,P=0.06),0.81 for breast feeding(95%CI=0.41～1.60,P=0.54),1.28 for allergic rhinitis(95%CI=1.05～1.57,P=0.02),3.49 for high adenoid grading(95%CI=2.69～4.53,P<0.01),1.11 for tonsil hypertrophy(95%CI=0.70～1.77,P=0.65),1.51 for history of passive smoking(95%CI=0.92～2.49,P=0.11),0.99 for gender(95%CI=0.86～1.13,P=0.83),and 0.40 for BMI(95%CI=-1.28～0.49,P=0.38).Conclusion Risks for SOM include young age,duration of disease,allergic rhinitis and adenoid grading in patients with AH.Identification of these risk factors can facilitate early effective preventive interventions to improve patients'quality of life.关键词
分泌性中耳炎/腺样体肥大/危险因素/Meta分析Key words
secretory otitis media/adenoid hypertrophy/risk factors/Meta analysis
