中国现代医生2025，Vol.63Issue(17)：1-3,24,4.DOI:10.3969/j.issn.1673-9701.2025.17.001
颈项透明层增厚胎儿不良妊娠结局分析
Analysis of adverse pregnancy outcomes in fetuses with thickening of the nuchal translucency
摘要
Abstract
Objective To investigate the adverse pregnancy outcomes of fetuses with increased nuchal translucency(NT).Methods A total of 376 pregnant women at the Third Affiliated Hospital of Zhengzhou University from May 2023 to January 2024 were selected as research subjects,who had a diagnosis of fetal NT ≥ the 95th percentile and complete pregnancy outcomes for singleton pregnancies.The fetuses were divided into simple thickening group(n=320)and thickening with structural abnormalities group(n=56)based on NT ultrasound results.The interventional prenatal diagnosis outcomes and pregnancy outcomes of two groups were compared.Results The rate of chromosomal abnormalities and the incidence of adverse pregnancy outcomes were higher in thickening with structural abnormalities group compared to simple thickening group with statistically significant differences(P＜0.05).The overall incidence of adverse pregnancy outcomes in NT thickened fetuses was 31.65％,but after excluding chromosomal abnormalities and structural malformations,the good pregnancy outcome rate in NT thickened fetuses was 98.09％.Conclusion NT thickening is associated with adverse pregnancy outcomes in fetuses,and the risk of poor fetal outcome is further increased when NT thickening combined with structural abnormalities in early pregnancy,but the pregnancy outcome is better in fetuses with NT thickening after excluding chromosomal abnormalities and structural malformations.关键词
颈项透明层/产前诊断/结构畸形/妊娠结局Key words
Nuchal translucency/Prenatal diagnosis/Structural malformations/Pregnancy outcome分类
医药卫生引用本文复制引用
任亚蒙,白毛焕,欧阳学哲,王梦茹,韩笑,陈晓甜,张梦蝶,刘灵..颈项透明层增厚胎儿不良妊娠结局分析[J].中国现代医生,2025,63(17):1-3,24,4.基金项目
国家重点研发计划项目(2022YFC2703300) （2022YFC2703300）
