保健医学研究与实践2025，Vol.22Issue(3)：19-25,7.DOI:10.11986/j.issn.1673-873X.2025.03.04
基于定量CT分析重庆地区人群内脏脂肪面积与代谢综合征的关系
Relationship between visceral fat area and metabolic syndrome in the Chongqing population based on quantitative CT analysis
摘要
Abstract
Objective To investigate the association between visceral fat area(VFA)and metabolic syndrome(MetS)using quantitative computed tomography(QCT)body-composition measurement.Methods We retrospectively reviewed the health-check data of 5,950 individuals(3,317 men and 2,633 women)who underwent QCT body-composition analysis at the Health Medicine Center of the Second Affiliated Hospital of Chongqing Medical University from July 2020 to July 2022.VFA and liver fat content(LFC)were measured by QCT,and clinical parameters including height,body weight,body mass index(BMI),waist circumference(WC),systolic and diastolic blood pressure(SBP,DBP),triglycerides(TG),total cho-lesterol(TC),high-density and low-density lipoprotein cholesterol(HDL-C,LDL-C),serum uric acid(SUA),and fasting blood glucose(FBG)were collected.We compared VFA between MetS and non-MetS groups stratified by sex,performed multivariable logistic regression with stepwise adjustment for confounders to construct three predictive models,and evalua-ted their performance using receiver operating characteristic(ROC)curves.Results The prevalence of MetS was signifi-cantly higher in men than in women(26.56%vs.9.99%).In both sexes,MetS patients were older and had higher BMI,WC,SBP,DBP,TG,SUA,FBG,and LFC,and lower HDL-C compared with non-MetS participants(P<0.05),while TC and LDL-C did not differ significantly between groups(P>0.05).VFA was markedly greater in the MetS group than in the non-MetS group,and higher VFA levels were associated with increased MetS risk;this trend persisted after sequential adjustment for confounders(P<0.05).VFA showed good predictive ability for MetS,with even stronger performance in women.Conclusion VFA appears to be an independent risk factor for MetS and may serve as a sensitive predictor for early MetS detection,demonstrating robust predictive efficacy.关键词
定量CT/内脏脂肪面积/代谢综合征Key words
Quantitative CT/Visceral fat area/Metabolic syndrome分类
医药卫生引用本文复制引用
陈梦雪,陈曜,王丽华,陈英,王凌云,李选..基于定量CT分析重庆地区人群内脏脂肪面积与代谢综合征的关系[J].保健医学研究与实践,2025,22(3):19-25,7.基金项目
重庆市科卫联合医学科研项目(2021MSXM057). （2021MSXM057）
