临床与病理杂志2025，Vol.45Issue(3)：354-364,11.DOI:10.11817/j.issn.2095-6959.2025.241009
NLR、PLR和SII与肝胆外科疾病
NLR,PLR,and SII and hepatobiliary surgical diseases
李萱萱 1王新乐 1王昕 1孙渊洁 1杨易戎 2刘宏2
作者信息
- 1. 山西医科大学第一临床医学院,太原 030001
- 2. 山西医科大学第一医院肝胆胰外科及肝脏移植中心,太原 030001
- 折叠
摘要
Abstract
Inflammatory responses play a crucial role in the onset and progression of various hepatobiliary surgical diseases.The neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),and systemic immune-inflammation index(SII)are important indicators reflecting systemic inflammatory status,and their clinical significance in hepatobiliary diseases has become increasingly recognized.Studies have shown that individual inflammatory markers,NLR,PLR,and SII,have prognostic value in diseases such as liver cancer,gallbladder carcinoma,and extrahepatic cholangiocarcinoma.Elevated levels of these markers are associated with poorer outcomes and can serve as independent prognostic risk factors.Compared to individual markers,the combined use of NLR,PLR,and SII scores has demonstrated superior predictive power in assessing prognosis for hepatocellular carcinoma and liver transplant patients.As simple and cost-effective inflammatory indicators,NLR,PLR,and SII offer new perspectives for clinical diagnosis,treatment,and personalized prognostic assessment in hepatobiliary surgery.关键词
炎症指数/肝癌/胆囊癌/肝外胆管癌/肝移植Key words
inflammatory index/liver cancer/gallbladder carcinoma/extrahepatic cholangiocarcinoma/liver transplantation引用本文复制引用
李萱萱,王新乐,王昕,孙渊洁,杨易戎,刘宏..NLR、PLR和SII与肝胆外科疾病[J].临床与病理杂志,2025,45(3):354-364,11.
