武警医学2025，Vol.36Issue(6)：483-486,4.
两种方式注射A型肉毒毒素对治疗雄激素性脱发的疗效
Clinical efficacy of two different injection methods of botulinum toxin A in treatment of androgenetic alopecia
冯歆越 1赵梓纲 2于水 2李承新3
作者信息
- 1. 100853 北京,解放军医学院||572013 三亚,解放军总医院海南医院皮肤科
- 2. 572013 三亚,解放军总医院海南医院皮肤科
- 3. 100853 北京,解放军医学院
- 折叠
摘要
Abstract
Objective To explore the clinical efficacy of two different injection methods of botulinum toxin A in the treatment of androgenetic alopecia.Methods A retrospective analysis was conducted on 28 male patients with androgenetic alopecia who re-ceived botulinum toxin A treatment at the department of dermatology of Hainan Hospital of PLA General Hospital from April 2023 to April 2024.A total of 28 patients were included in this study,and they were divided into groups based on different treatment methods,with 15 patients receiving intramuscular injection(intramuscular injection group),and 13 patients receiving intramuscular injection combined with intradermal injection(combined injection group).Clinical efficacy was assessed after 24 weeks of treatment using three evaluation methods:self-assessment,appearance evaluation,and hair count assessment.Results There was no statistically signifi-cant difference in self-assessment,the improvement of scalp oiliness and hair growth between the two groups(P>0.05).The effec-tive rate of intramuscular injection group was 60%,and that of the combined group was 69.2%,with no statistically significant dif-ference(P>0.05).In hair count assessment,both groups showed a significant increase in hair count after treatment compared to before treatment(P<0.05).At week 24 of treatment,the combined injection group showed superior results compared to the intra-muscular injection group[(176.2±44.9)vs.(160.5±31.3)],with statistically significant difference(P<0.05).Conclusions Both intramuscular injection and combined intramuscular and intradermal injection of botulinum toxin A are effective in the treatment of androgenetic alopecia,and the combined injection method is more effective.关键词
A型肉毒毒素/雄激素性脱发/治疗应用/肌内注射/皮内注射Key words
botulinum toxin A/androgenetic alopecia/therapeutic use/intramuscular injection/intradermal injection分类
医药卫生引用本文复制引用
冯歆越,赵梓纲,于水,李承新..两种方式注射A型肉毒毒素对治疗雄激素性脱发的疗效[J].武警医学,2025,36(6):483-486,4.
