武警医学2025，Vol.36Issue(6)：496-500,520,6.
经皮椎体成形术治疗骨质疏松性椎体压缩性骨折疗效的Meta分析
Meta-analysis of the efficacy of percutaneous vertebroplasty in the treatment of osteopo-rotic vertebral compression fractures under different surgical timing
武春雷 1胡文 1张红 1王昊1
作者信息
- 1. 300142 天津,联勤保障部队第983医院骨科
- 折叠
摘要
Abstract
Objective To investigate the efficacy and safety of percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures under different surgical timing.Methods Comprehensive search was conducted in both Chinese and English databases such as VIP Chinese Journal Service Platform,China National Knowledge Infrastructure(CNKI),Wanfang Medi-cal Network,PubMed,Embase,Scopus,and Web of Science.The efficacy differences of vertebroplasty in patients at the acute,subacute,and chronic stages were compared.Mean differences(MDs)and risk differences(RDs)were employed as combined vari-ables,and 95%was selected as the confidence interval(CI).Results A total of 9 clinical studies were included,involving 678 pa-tients.The findings showed that early percutaneous vertebroplasty could reduce the incidence of postoperative vertebral refracture compared with delayed surgery(RD:-0.13;95%CI:-0.21～-0.05;P=0.002),and had more advantages in postoperative Cobb angle recovery(MD:-5.96;95%CI:-11.78～-0.14;P=0.04),while the volume of injected vertebral bone cement in delayed sur-gery was notably lower(MD:1.24;95%CI:0.57～1.91;P=0.0003).There were no significant differences between the two groups regarding postoperative bone cement leakage,VAS scores,and ODI indices.Conclusions In the treatment of osteoporotic vertebral compression fractures,early percutaneous vertebroplasty can effectively decrease the incidence of postoperative vertebral refracture and achieve better postoperative Cobb angle,although the amount of bone cement injection is smaller after delayed surgery.关键词
经皮椎体成形术/手术时机/骨质疏松性椎体压缩骨折/Meta分析Key words
percutaneous vertebroplasty/surgical timing/osteoporotic vertebral compression fracture/Meta-analysis分类
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武春雷,胡文,张红,王昊..经皮椎体成形术治疗骨质疏松性椎体压缩性骨折疗效的Meta分析[J].武警医学,2025,36(6):496-500,520,6.
