Protective effect of Dan Ze mixture(丹泽合剂)against lipotoxic cardiomyopathy through activating B-cell lymphoma-2 adenovirus E1B 19 kDa-interacting protein 3/mitophagy signaling pathway
Protective effect of Dan Ze mixture(丹泽合剂)against lipotoxic cardiomyopathy through activating B-cell lymphoma-2 adenovirus E1B 19 kDa-interacting protein 3/mitophagy signaling pathway
摘要
关键词
mitophagy/signal transduction/Dan Ze mixture/lipotoxic cardiomyopathy/mitochondrial autophagy/Bcl2/adenovirus E1B gene 19 kDa protein-interacting protein 3Key words
mitophagy/signal transduction/Dan Ze mixture/lipotoxic cardiomyopathy/mitochondrial autophagy/Bcl2/adenovirus E1B gene 19 kDa protein-interacting protein 3引用本文复制引用
..Protective effect of Dan Ze mixture(丹泽合剂)against lipotoxic cardiomyopathy through activating B-cell lymphoma-2 adenovirus E1B 19 kDa-interacting protein 3/mitophagy signaling pathway[J].中医杂志（英文版）,2025,45(3):538-551,14.基金项目
Supported by Scientific Research Project of Hebei Province Administration of Traditional Chinese Medicine:to Explore the Protective Effect and Mechanism of Zexie Decoction on Lipotoxic Cardiomyopathy based on the p-mitogen-activated protein kinases/Peroxisome proliferator-activated receptor γ coactivator 1-alpha(pMAPK/PGC-1α)Signaling Pathway(No.2022096),Medical Science Research Project of Hebei Province:the Effect of 23-acetyl Alismol-B on Mitochondrial Function in Palmitic Acid-induced H9c2 Cells Was Investigated based on the Ca2+-Cyclic Adenosine Monophosphate(cAMP)-Response Element Binding Protein/cAMP Response Element(CREB/CRE)-PGC-1α Signaling Pathway(No.20221490),Hebei province natural science fund project:Study on the Mechanism of Danshen Zexie Decoction in Activating Nuclear Factor Erythroid 2-related Factor 2 Signaling Pathway to Trigger Omi/HtrA2,Restoring Autophagic Flux and Enhancing Metabolism-Related Fatty Liver Disease(No.H2023423064)and Hebei graduate student innovation ability funding training project:to Investigate the Protective Effects and Underlying Mechanisms of Zexie Decoction on Lipotoxic Cardiomyopathy,with A Focus on the PGC-1a Signaling Pathway(No.CXZZBS2022096) （pMAPK/PGC-1α）
