阿尔茨海默病及相关病2025，Vol.8Issue(4)：248-252,5.DOI:10.3969/j.issn.2096-5516.2025.04.005
以肌张力障碍为首发症状的疑似克-雅病1例报告
A case report of sCJD manifested as muscle dystonia
简文佳 1申少珍 1杨贺 1甄飞 1窦金娟1
作者信息
- 1. 北京中医药大学东直门医院,北京 101100
- 折叠
摘要
Abstract
Objective:To investigate the characteristic of sporadic Creutzfeldt-Jakob disease(sCJD),improve the knowledge of sCJD for clinicians.Methods:We collected the clinical data,brain neuroimages and laboratory test results of a case of sCJD and reviewed relative articles.Results:The patient showed limb rigidity,involuntary movements,myoclonic jerks,speech disorders,rapidly progressive cognitive impairment,and later autonomic dysfunction,and passed away 8 months after the onset.Conclusion:The early symptoms of sCJD are atypical,varied and heterogeneous,with a high fatality rate.The diagnosis of CJD requires attention to distinguishing it from various diseases,and dynamic examination of cerebrospinal fluid,brain MRI,electroencephalogram,and even biopsy to avoid misdiagnosis and missed diagnosis.关键词
克-雅病/诊断/鉴别诊断Key words
Creutzfeldt-Jakob disease/Diagnosis/Differential diagnosis分类
医药卫生引用本文复制引用
简文佳,申少珍,杨贺,甄飞,窦金娟..以肌张力障碍为首发症状的疑似克-雅病1例报告[J].阿尔茨海默病及相关病,2025,8(4):248-252,5.
