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阿尔茨海默病和骨质疏松共病的机制、危险因素和治疗研究进展

荆超楠 王江波 张冠群

阿尔茨海默病及相关病2025,Vol.8Issue(4):278-284,7.
阿尔茨海默病及相关病2025,Vol.8Issue(4):278-284,7.DOI:10.3969/j.issn.2096-5516.2025.04.010

阿尔茨海默病和骨质疏松共病的机制、危险因素和治疗研究进展

Research progress on mechanisms,risk factors and treatment of comorbidity of Alzheimer's disease and osteoporosis

荆超楠 1王江波 2张冠群2

作者信息

  • 1. 徐州医科大学附属临床学院神经内科,江苏 徐州 221004
  • 2. 东南大学附属徐州中心医院神经内科,江苏 徐州 221000
  • 折叠

摘要

Abstract

Alzheimer's disease(AD)and osteoporosis(OP)are both age-related degenerative diseases,which mainly occur in the elderly population over the age of 60,and are becoming an increasingly common combination in the aging population.It has been proved that a variety of factors can stimulate and accelerate the occurrence of AD and OP in clinical practice.This review mainly studies the common pathogenesis of AD and OP,and discusses the pathogenesis factors such as vitamin D and vitamin K levels,signaling pathways,apolipoprotein and neuroinflammation in AD mouse models.In addition,potential treatments for these two diseases are described.

关键词

阿尔茨海默病/骨质疏松/信号通路/维生素/神经炎症

Key words

Alzheimer's disease/Osteoporosis/Signal path/Vitamin/Neuroinflammation

分类

医药卫生

引用本文复制引用

荆超楠,王江波,张冠群..阿尔茨海默病和骨质疏松共病的机制、危险因素和治疗研究进展[J].阿尔茨海默病及相关病,2025,8(4):278-284,7.

阿尔茨海默病及相关病

2096-5516

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