北京中医药2025，Vol.44Issue(6)：717-720,4.DOI:10.16025/j.1674-1307.2025.06.009
苍肤洗剂干纸巾外用治疗手足癣的临床观察
Clinical observation on the external use of Cangfu Lotion with dry tissues for the treatment of tinea manuum and pedis
摘要
Abstract
Objective To observe the clinical efficacy and safety of the external application of Cangfu Lotion with dry tissues,a traditional Chinese medicine(TCM)formula based on the experience of renowned physician ZHAO Bingnan,in the treatment of tinea manuum and pedis.Methods A prospective,randomized,controlled study was conducted involving 144 patients with tinea manuum and pedis treated at the Dermatology Outpatient Department of Beijing Hospital of Traditional Chinese Medicine from January 2022 to December 2023.Patients were randomly assigned by a random number table to Group A,Group B,or Group C.Group A was treated with Cangfu Lotion decoction soaking,Group B received dry tissues soaked in Cangfu Lotion for daily application,and Group C was treated with topical terbinafine cream.Each group underwent treatment for one week per course,for two consecutive courses.The efficacy was compared among the three groups by evaluating lesion area,itching severity score,lesion severity score,fungal clearance rate,adverse reactions,and recurrence rate before and after treatment.Results There was no statistically significant difference in the total effective rate among the three groups(P>0.05).After treatment,lesion area,itching severity score,and lesion severity score were significantly improved in all three groups compared to those before treatment(P<0.01).Significant differences were found among the three groups in lesion area and lesion severity score after treatment(P<0.05).Pairwise comparison showed that the lesion area in Group A was smaller than that in Group B(P<0.05),and lesion severity scores in Groups A and B were lower than those in Group C(P<0.01).No statistically significant differences were found among the groups in fungal clearance rate or incidence of adverse reactions.Recurrence rates in Groups A and B were lower than in Group C,but the difference was not statistically significant(P>0.05).Conclusion External application of Cangfu Lotion is effective and safe in treating tinea manuum and pedis.The patented dry tissue technology applied in TCM external treatment improves convenience and portability.关键词
苍肤洗剂/药物干纸巾/中医外治/手足癣Key words
Cangfu Lotion/dry tissue medication/traditional Chinese medicine external treatment/tinea manuum and pedis引用本文复制引用
王倩,邓丙戌,蔡念宁,曲剑华,周冬梅..苍肤洗剂干纸巾外用治疗手足癣的临床观察[J].北京中医药,2025,44(6):717-720,4.基金项目
北京中医药薪火传承"新3+3"工程示范案例项目——燕京赵氏皮科流派名医代传(2023-ZYSF-05) （2023-ZYSF-05）
国家中医药管理局全国中医学术流派传承工作室项目——燕京赵氏皮科流派传承工作室(LPGZS2012-03) （LPGZS2012-03）
