现代中医临床2025，Vol.32Issue(4)：6-11,6.DOI:10.3969/j.issn.2095-6606.2025.04.002
阈下抑郁患者中医证候和体质研究
A study on the TCM patterns and constitutions of patients with subthreshold depression
摘要
Abstract
Objective To explore the distribution and correlation of Traditional Chinese Medicine(TCM)patterns and constitutions in patients with subthreshold depression(SD).Methods A total of 521 patients diagnosed with SD were screened from the Physical Examination Departments of eight tertiary hospitals in five cities.Their TCM constitutions and patterns were determined through questionnaires,and data analysis was performed using SPSS 26.0 and SPSS Modeler 18.0.Results The majority of the SD patients exhibit unbalanced constitutions,predominantly characterized by the Qi-Stagnation,Yang-Deficiency,and Qi-Deficiency type.The elderly patients with SD are mainly characterized by Qi-Stagnation,Qi-Deficiency and Yang-Deficiency.The young and middle-aged SD patients are mainly characterized by Qi-Stagnation and Yang-Deficiency.According to the support degree,the top 20 rules were sorted from high to low,and the combination of Qi-Stagnation and Qi-Deficiency was the most closely related.The TCM pattern scores of the SD patients across different age groups were analyzed.The result indicated significant differences in the pattern scores for heart-spleen deficiency,liver-kidney yin deficiency,internal phlegm-turbidity accumulation,heart-liver fire exuberance,and qi stagnation with blood stasis among the various age groups(P<0.05).Pairwise comparisons within groups revealed that the scores for the liver qi stagnation and spleen deficiency patterns,as well as internal phlegm-turbidity accumulation,were significantly different between the middle-aged and elderly groups(P<0.05).Additionally,there were significant differences in the scores for the heart-spleen deficiency and liver-kidney yin deficiency types between the elderly and middle-aged groups,as well as between the elderly and young groups(P<0.05).Furthermore,significant differences were observed in the scores for the heart-liver fire exuberance and qi stagnation with blood stasis patterns between the middle-aged and young groups,as well as between the middle-aged and elderly groups(P<0.05).Correlation analysis between different TCM patterns and constitutions in SD patients showed that:there was a negative correlation between the Balanced constitution and TCM pattern.The positive correlation coefficient between liver stagnation and spleen deficiency and heart-spleen deficiency was 0.45,the positive correlation coefficient between liver-kidney yin deficiency and heart-liver fire exuberance was 0.38,the positive correlation coefficient between the Phlegm-Dampness constitution and Damp-Heat was 0.71,and the positive correlation coefficient between Qi-Stagnation and Qi-Deficiency was 0.66.The positive correlation coefficient between Yin-Deficiency,Phlegm-Dampness and yin deficiency of the liver and kidney syndrome was 0.27,0.24,respectively.The positive correlation coefficient between Phlegm-Dampness and internal phlegm-turbidity accumulation was 0.23.Conclusion Individuals with SD exhibit significant inclinations for specific TCM constitutions,with Qi-Stagnation,Yang-Deficiency,and Qi-Deficiency accounting for a relatively high proportion.And the main manifestations of TCM patterns include liver qi stagnation and spleen deficiency,and heart-liver fire exuberance.Significant positive constitution-pattern correlations were identified,except for Balanced constitution.关键词
阈下抑郁/中医体质/证候/相关性Key words
subthreshold depression/TCM constitutions/TCM patterns/correlation分类
医药卫生引用本文复制引用
胡文悦,林彬,钟碧莹,王振亦,常泽,陈润铭,何玉瑶,熊涛,韩振蕴..阈下抑郁患者中医证候和体质研究[J].现代中医临床,2025,32(4):6-11,6.基金项目
国家重点研发计划(No.2019YFC1710103) （No.2019YFC1710103）
深圳市"医疗卫生三名工程"项目(No.SZZYSM202105010) （No.SZZYSM202105010）
深圳市龙岗区医学重点学科 （）
