长春中医药大学学报2025,Vol.41Issue(7):713-718,6.DOI:10.13463/j.cnki.cczyy.2025.07.002
基于"正虚毒泛"探讨肺癌肿瘤微环境的中医内涵及重塑策略
Exploration of traditional Chinese medicine connotation and remodeling strategy of lung cancer tumor microenvironment based on healthy qi dificiency and blazing toxin
摘要
Abstract
"Healthy qi dificiency and blazing toxin"is the core pathogenesis of lung cancer.Healthy qi dificiency is the basic condition for initiating lung cancer,and the dynamic pathogenesis of lung cancer progression is"accumulation of pathogenic factors and blazing toxin".The tumor microenvironment(TME)presents a cancer-promoting state such as immunosuppression,high pressure,hypoxia,chronic inflammation,and low pH under stress conditions.Under the concept of"healthy qi dificiency and blazing toxin",there are similarities between the occurrence and development of lung cancer and the abnormal state of TME.This article will discuss the commonness of"healthy qi dificiency and blazing toxin-TME"in the pathogenesis of lung cancer,and propose traditional Chinese medicine strategies for remodeling lung cancer TME,in order to provide new ideas for the prevention and treatment of lung cancer.关键词
肺癌/正虚毒泛/肿瘤微环境/中医内涵/治疗策略Key words
lung cancer/Healthy qi dificiency and blazing toxin/tumor microenvironment/connotation of traditional Chinese medicine/treatment strategy分类
医药卫生引用本文复制引用
吴思雨,庞雪莹,隋博文..基于"正虚毒泛"探讨肺癌肿瘤微环境的中医内涵及重塑策略[J].长春中医药大学学报,2025,41(7):713-718,6.基金项目
国家中医药管理局第五批全国中医临床优秀人才项目(国中医药人教函[2022]1号) (国中医药人教函[2022]1号)