长春中医药大学学报2025，Vol.41Issue(7)：723-727,5.DOI:10.13463/j.cnki.cczyy.2025.07.004
基于"瘀毒损络"辨治冠状动脉微血管病变
Treatment based on syndrome differentiation of coronary microvascular disease based on stasis-toxin damage to the collaterals
摘要
Abstract
Based on the correlation between the pathogenic characteristics of the theory of stasis-toxin damage to the collaterals and the incidence of coronary microvascular disease,the pathological process of coronary microvascular disease is summarized as the accumulation of blood stasis in the collaterals for a long time,stasis-toxin transformation,and the damage to the heart collaterals caused by the combination of stasis-toxin.Therefore,it is established that the core pathogenesis of coronary microvascular disease is stasis-toxin damage to the collaterals,and detoxification and activating blood circulation are the fundamental treatment of this disease.The clinical syndromes of coronary microvascular disease are complicated and varied,and the pathological factors are mixed with each other.On the basis of detoxification and activating blood circulation,emphasis is placed on treating both manifestation and root cause of disease,taking into account the different syndromes such as benefiting qi and consolidating body resistance,warming yang and resolving phlegm,and dispersing liver and regulating qi.The long-term course of the disease,lingering and difficult to heal,and the difficulty of stasis-toxin cementation should be improved by utilizing the characteristics of insect drugs to break blood stasis and detoxify to enhance clinical efficacy.关键词
冠状动脉微血管病变/瘀毒损络/解毒活血/益气固本/温阳化痰/疏肝理气Key words
coronary microvascular disease/stasis-toxin damage to the collaterals/detoxification and activating blood circulation/benefiting qi and consolidating body resistance/warming yang and resolving phlegm/dispersing liver and regulating qi分类
医药卫生引用本文复制引用
周莉君,杨圣洁,王昕玥,吴敏..基于"瘀毒损络"辨治冠状动脉微血管病变[J].长春中医药大学学报,2025,41(7):723-727,5.基金项目
国家自然科学基金项目(82074254,82374281) （82074254,82374281）
北京市自然科学基金项目(7172185) （7172185）
中国中医科学院科技创新工程项目(CI2021A01413) （CI2021A01413）
第五批中医临床优秀人才研修项目(国中医药人才函[2022]1号) （国中医药人才函[2022]1号）
北京市中医药科技发展资金项目(BJZYYB-2023-73) （BJZYYB-2023-73）
首都卫生发展科研专项项目自主创新(首发2024-2-4154) （首发2024-2-4154）
