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重构本草——马钱子

滑成龙 陈颖 米文静 薛崇祥

长春中医药大学学报2025,Vol.41Issue(7):728-731,4.
长春中医药大学学报2025,Vol.41Issue(7):728-731,4.DOI:10.13463/j.cnki.cczyy.2025.07.005

重构本草——马钱子

Reconstruction of Chinese materia medica-Nux vomica

滑成龙 1陈颖 2米文静 3薛崇祥4

作者信息

  • 1. 成都中医药大学药学院,成都 611137
  • 2. 北京中医药大学,北京 100029
  • 3. 中国中医科学院广安门医院代谢病研究所,北京 100053
  • 4. 浙江大学医学院附属第二医院内分泌科,杭州 310009
  • 折叠

摘要

Abstract

Through investigation of ancient books and the sorting of modern research achievements of traditional Chinese medicine,combined with the understanding and application experience of famous experts and scholars in desciplinary fields such as traditional Chinese medicine clinical medicine and science of Chinese materia medica,it is concluded that nux vomica mainly has the effects of unblocking collaterals and relieving pain,dispersing nodules and reducing swelling.The symptom target is joint pain.The biochemical indicator target is tumor and neuromuscular junction transmission disorders.Modern pharmacological studies have found that nux vomica and its active ingredients have anti-inflammatory and analgesic effects,exciting the nervous system,regulating immunity,and anti-tumor effects.The main toxic component is strychnine.The use of processed nux vomica can reduce toxicity and ensure medication safety.The commonly used dosage in clinical practice is 0.3-0.6 g.This medicine is processed into pills or powders for administration.

关键词

马钱子/症靶/标靶/重构本草/临床回归

Key words

nux vomica/symptom target/biochemical indicator target/reconstruction of Chinese materia medica/clinical verification

分类

医药卫生

引用本文复制引用

滑成龙,陈颖,米文静,薛崇祥..重构本草——马钱子[J].长春中医药大学学报,2025,41(7):728-731,4.

基金项目

国家自然基金委-中国科学院联合项目资助中西医结合创新范式战略研究(XK2023SMC003) (XK2023SMC003)

长春中医药大学学报

2095-6258

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