动物模型与实验医学(英文)2025,Vol.8Issue(6):1023-1032,10.DOI:10.1002/ame2.12562
Application of humanized mice in the safety experiments of antibody drugs
Application of humanized mice in the safety experiments of antibody drugs
Zhimin Sun 1Naping Tang 2Mengyun Gu 3Zixuan Yang 3Lei Shi 3Liyuan Zhao 1Minhui Zheng 3Yan Wang 4Wei Zhang 1Kexin Han1
作者信息
- 1. College of Pharmacy,Anhui University of Chinese Medicine,Hefei,China||InnoStar Bio-Tech Nantong Co.,Ltd.,Nantong,China||Yangtze Delta Drug Advanced Research Institute,Yangtze Delta Pharmaceutical College,Nantong,China
- 2. Yangtze Delta Drug Advanced Research Institute,Yangtze Delta Pharmaceutical College,Nantong,China||China State Institute of Pharmaceutical Industry,Shanghai Innostar Bio-Technology Co.,Ltd.,Shanghai,China
- 3. China State Institute of Pharmaceutical Industry,Shanghai Innostar Bio-Technology Co.,Ltd.,Shanghai,China
- 4. InnoStar Bio-Tech Nantong Co.,Ltd.,Nantong,China||China State Institute of Pharmaceutical Industry,Shanghai Innostar Bio-Technology Co.,Ltd.,Shanghai,China
- 折叠
摘要
关键词
antibody drugs/humanized mice/immunogenicity/preclinical evaluationKey words
antibody drugs/humanized mice/immunogenicity/preclinical evaluation引用本文复制引用
Zhimin Sun,Naping Tang,Mengyun Gu,Zixuan Yang,Lei Shi,Liyuan Zhao,Minhui Zheng,Yan Wang,Wei Zhang,Kexin Han..Application of humanized mice in the safety experiments of antibody drugs[J].动物模型与实验医学(英文),2025,8(6):1023-1032,10.基金项目
Independent Research and Development Projects Foundation of Shanghai InnoStar Bio-Techology Co.Ltd,Grant/Award Number:H23ZZYF01 and H24ZZYF01 ()