动物营养学报2025，Vol.37Issue(7)：4265-4273,9.DOI:10.12418/CJAN2025.349
胆汁酸与肠道微生物协同调控机制及其对机体健康的影响
Co-Regulation Mechanism of Bile Acids and Gut Microbiota and Its Significance for Body Health
摘要
Abstract
Bile acids,as a kind of key bioactive molecule,not only participate in glucose and lipid metabo-lism,but also play the role of a signal bridge between the host and gut microbiota.The gut microbiota is close-ly related to liver metabolism and intestinal health.It utilizes its unique metabolic capacity to influence the syn-thesis,transformation and signal transduction of bile acids,thereby playing a significant role in the host's met-abolic state.This article reviews how gut microbiota affect bile acid metabolism and its receptors,and deeply explores the regulatory mechanism of the gut microbiota-bile acid axis on enterohepatic diseases,aiming to pro-vide a reference for the development of precise nutritional regulatory measures targeting the gut microbiota to prevent or alleviate related diseases and protect intestinal health.[Chinese Journal of Animal Nutrition,2025,37(7):4265-4273].关键词
肠道微生物/胆汁酸/调控机制/肠道健康Key words
gut microbiota/bile acids/regulation mechanism/intestinal health分类
农业科技引用本文复制引用
郭世娇,宫旭,骆超超,童津津..胆汁酸与肠道微生物协同调控机制及其对机体健康的影响[J].动物营养学报,2025,37(7):4265-4273,9.基金项目
国家自然科学基金项目(32272904) （32272904）
