纺织高校基础科学学报2025，Vol.38Issue(3)：1-13,13.DOI:10.13338/j.issn.1006-8341.2025.03.001
丝胶蛋白在生物医用材料中的研究进展与展望
Research progress and prospect of sericin in biomedical materials
摘要
Abstract
Sericin protein,a vital natural macromolecular component of silk,has demonstrated sub-stantial potential in biomedical materials owing to its exceptional biocompatibility,cell-adhesive properties,tunable degradation kinetics,and abundant active functional groups enabling facile mod-ification.This review systematically delineates the core characteristics of sericin as a biomaterial and critically analyzes the advantages,limitations,and technical bottlenecks of primary extrac-tion methodologies.Emphasis is placed on the development and applications of diversified sericin-based material formats,including hydrogels,films,nerve conduits,scaffolds,microneedles,mi-crospheres,and flexible wearable electronics in tissue engineering and regenerative medicine.Fu-ture research directions encompass:developing mild and efficient extraction techniques,elucida-ting structure-function relationships of bioactive sericin peptides,enhancing mechanical proper-ties through nanocomposite strategies,advancing exploration of smart-responsive materials,3D-printed bioinks,and implantable electronics,and facilitating the transition of sericin from a tex-tile byproduct to a high-value-added biomaterial.关键词
丝胶蛋白/生物医用/组织工程/再生医学Key words
sericin protein/biomedical application/tissue engineering/regenerative medicine分类
轻工纺织引用本文复制引用
杨萌,王永超,蓝广芊..丝胶蛋白在生物医用材料中的研究进展与展望[J].纺织高校基础科学学报,2025,38(3):1-13,13.基金项目
四川省科技计划资助(2024ZYD0177) （2024ZYD0177）
