高等学校化学学报2025，Vol.46Issue(8)：35-42,8.DOI:10.7503/cjcu20250057
催化剂调控多元醇与2-硝基芳烃的选择性氢转移反应
Catalyst-modulated Selective Hydrogen Transfer Reactions of Polyols with 2-Nitroaromatics
摘要
Abstract
The selective conversion of biomass-derived polyols into nitrogen-containing compounds remains a formidable challenge in sustainable chemistry.Although hydrogen borrowing strategies have emerged as environmen-tally benign alternatives to traditional reductive amination,precise control over selective C—C bond cleavage during polyol conversion persists as a significant difficulty.Herein,we report an approach utilizing distinct catalytic systems to regulate selective C—C bond cleavage of polyols,thereby generating diverse nitrogen-containing compounds.This system efficiently synthesizes quinoxaline and indole-type N-heterocyclic compounds under mild conditions without requiring external reducing agents.Substrate scope studies demonstrate that both electron-rich and electron-deficient aromatic amines and indole substrates afford the target products in moderate to excellent yields.This strategy over-comes the reliance of traditional reductive amination on harsh conditions and external reductants,thus providing a new,atom-economical,and environmentally benign pathway for biomass transformation.关键词
多元醇/氢转移策略/N-杂环化合物Key words
Polyols/Hydrogen transfer strategy/N-heterocyclic compounds分类
化学化工引用本文复制引用
张瑶瑶,刘珊珊..催化剂调控多元醇与2-硝基芳烃的选择性氢转移反应[J].高等学校化学学报,2025,46(8):35-42,8.基金项目
国家自然科学基金(批准号:22379087)资助.Supported by the National Natural Science Foundation of China(No.22379087). （批准号:22379087）
