赣南医科大学学报2025，Vol.45Issue(6)：530-533,596,5.DOI:10.3969/j.issn.1001-5779.2025.06.003
左束支区域起搏联合左心室心外膜起搏心脏再同步疗法的疗效分析
Efficacy analysis of left bundle branch area pacing combined with left ventricular epicardial pacing in cardiac resynchronization therapy
摘要
Abstract
Objective:To analyze the efficacy and the safety of left bundle branch area pacing combined with left ventricular epicardial pacing in cardiac resynchronization therapy(CRT).Methods:A total of 40 patients who received CRT treatment at The First Affiliated Hospital of Gannan Medical University from January 2019 to November 2023 were selected.The patients who received left bundle branch area pacing combined with left ventricular epicardial pacing were set as the experimental group(20 cases),and the patients who received traditional biventricular pacing CRT treatment were set as the control group(20 cases).All patients underwent device programming optimization to make the paced QRS duration as short as possible.Intraoperative pacemaker parameters,immediate postoperative QRS wave width,QRS wave width,left ventricular end diastolic diameter,left ventricular ejaculation fraction,and new adverse cardiovascular events were recorded between the two groups.Results:The left bundle branch electrode pacing threshold[(0.92±0.19)v]in the experimental group was higher than that in the control group[(0.74±0.19)v],and the difference was statistically significant(P=0.005).The R-wave sensing amplitude of the experimental group[(7.54±2.43)mv]was lower than that of the control group[(12.24±3.18)mv],and the difference was statistically significant(P＜0.001).The P-wave sensing amplitude[(3.45±0.85)mv]in the experimental group was higher than that in the control group[(2.64±1.00)mv],and the difference was statistically significant(P＜0.05).Compared with the control group,the immediate QRS wave width was narrower after surgery in the experimental group,and the QRS wave shortening rate was higher,and the differences were statistically significant(P＜0.05).Compared with the control group,the QRS wave was narrower in the 6-month postoperative period,the reduction of the left ventricular end-diastolic diameter was more significant and the increase of the left ventricular ejection fraction is more obvious,and the difference is statistically significant(P＜0.05).No new adverse cardiovascular events occurred within 6 months after the operation in the two groups.Conclusion:Compared with traditional biventricular pacing CRT treatment,the electrical synchronization of left bundle branch area pacing combined with left ventricular epicardial pacing CRT treatment is better,and the cardiac function improvement is more obvious.关键词
左束支区域起搏/左心室心外膜起搏/心脏再同步疗法/心脏起搏器,人工Key words
Left bundle branch area pacing/Left ventricular epicardial pacing/Cardiac resynchronization therapy/Pacemaker,artificial分类
医药卫生引用本文复制引用
王承傧,陈信光,盛珊慧,田克钧,黄琴,阳贻红..左束支区域起搏联合左心室心外膜起搏心脏再同步疗法的疗效分析[J].赣南医科大学学报,2025,45(6):530-533,596,5.基金项目
江西省卫生健康委员会科技计划项目(202310778) （202310778）
