国际医学放射学杂志2025，Vol.48Issue(4)：379-383,5.DOI:10.19300/j.2025.Z22086
超声微泡靶向治疗在肿瘤治疗相关心脏毒性中的研究进展
Research progress of ultrasound microbubbles in targeted therapy for cancer therapy-related cardiotoxicity
庄海明 1王吴婉 1王勇1
作者信息
- 1. 北京协和医学院中国医学科学院肿瘤医院超声科,北京 100021
- 折叠
摘要
Abstract
Cancer therapies may induce varying degrees of cardiac injury,leading to cancer therapy-related cardiovascular toxicity(CTR-CVT)that significantly impacts patient prognosis and long-term survival.Ultrasound microbubbles,as novel non-viral targeted delivery vehicles,exhibit unique physical properties,excellent biocompatibility,and ultrasound-triggered cavitation effects,demonstrating promising potential for CTR-CVT-targeted therapy.This review summarizes ultrasound microbubble characteristics and targeting mechanisms,with focus on recent advances in microbubble-mediated gene transfection and targeted drug delivery for systemic CTR-CVT treatment.关键词
超声微泡/肿瘤/靶向治疗/基因治疗/药物递送Key words
Ultrasound microbubbles/Cancer/Targeted therapy/Gene therapy/Drug delivery分类
医药卫生引用本文复制引用
庄海明,王吴婉,王勇..超声微泡靶向治疗在肿瘤治疗相关心脏毒性中的研究进展[J].国际医学放射学杂志,2025,48(4):379-383,5.
