摘要
Abstract
Objective To analyze the ultrasonographic features of intramuscular lipoma and various subtypes of liposarcoma and assess their value in differential diagnosis.Methods All of 66 patients with pathologically confirmed adipocytic tumors located in trunk or limb muscles were retrospectively analyzed.According to pathological results,patients were divided into a lipoma group(45 cases)and a liposarcoma group(21 cases).The tumor's shape,boundary,internal echo,degree of echo uniformity,presence of hypoechoic/anechoic areas,fine septations and blood flow signal grading were evaluated.The maximum diameter of tumor was recorded.Differences in clinical data and ultrasound features between the two groups were compared using the Mann-Whitney U test and chi-square test.Ultrasound parameters with statistical significance were further analyzed using receiver operating characteristic(ROC)curve to determine the area under the curve(AUC),sensitivity,and specificity.The ultrasonic characteristics of different liposarcoma subtypes were also analyzed.Results Compared with the lipoma group,the liposarcoma group had a significantly higher incidence of hypoechoic/anechoic areas,fine septations,and gradeⅠ-Ⅱblood flow signals,and showed larger maximum diameters(all P＜0.05).Blood flow signal grading demonstrated the best diagnostic efficacy(AUC=0.837)for distinguishing lipoma from liposarcoma,while the maximum diameter achieved the highest sensitivity(0.90),and the the presence of hypoechoic/anechoic area yielded the highest specificity(0.91).Ultrasonographically,well-differentiated liposarcoma often showed fine septations and sparse vascularity.Myxoid liposarcomas were characterized by heterogeneous internal echogenicity,with hypoechoic/anechoic areas and relatively abundant blood flow.Undifferentiated liposarcoma typically presented with hyperechoic and hypoechoic,with clear boundaries and relatively rich blood flow signals.Pleomorphic liposarcoma showed mixed echogenicity and relatively abundant blood flow.Conclusion Muscularis lipoma and liposarcoma have different ultrasonic characteristics,such as the maximum diameter,the presence of hypoechoic/anechoic region,the presence of fine septations,and the blood flow signal,which have high diagnostic value in differentiating between lipomas and liposarcomas.Different subtypes of liposarcoma exhibit distinct ultrasonic manifestations.关键词
超声/脂肪瘤/脂肪肉瘤/鉴别诊断Key words
Ultrasound/Lipoma/Liposarcoma/Differential diagnosis分类
医药卫生
