神经损伤与功能重建2025，Vol.20Issue(7)：395-401,7.DOI:10.16780/j.cnki.sjssgncj.20240161
细胞自噬在缺血性脑卒中作用的可视化分析
Visualization of the Role of Cellular Autophagy in Ischaemic Stroke
摘要
Abstract
Objective:To analyze and summarize the current research status and frontiers of the role of autophagy in ischemic stroke based on bibliometrics.Methods:Literature was retrieved from the core collections of the China National Knowledge Infrastructure(CNKI),Wanfang Data,and Web of Science databases.Software tools such as Cite Space,VOS viewer,and the bibliometric package Bibliometrix in R language were employed to conduct visual analyses on the number of publications,contributing countries,author collaborations,institutional collaborations,keywords,and co-occurrence networks of the published literature from 2013 to 2023.Results:The number of included Chinese and English publications has shown a stable trend in recent years,with an upward trajectory observed,indicating sustained research interest.China ranks first in terms of the number of publications.TIAN Fuling and CHEN Zhong are the most prolific authors in Chinese and English literature,respectively.Anhui University of Chinese Medicine and Zhejiang University are the institutions with the highest number of publications in Chinese and English literature,respectively.Research hotspots in the coming years may include the combination of traditional Chinese medicine(TCM),exosomes,crosstalk effects,and mechanistic studies.Conclusion:Future research by scientists should delve deeper into the specific mechanisms and effects of autophagy,as well as the development of innovative drugs derived from TCM.Methods such as gene knockout and network pharmacology can be utilized to explore the specific mechanisms of action.The strategy of"target identification through drugs"in TCM can be attempted to elucidate the pharmacodynamic substances of TCM,reveal new TCM targets,and develop innovative TCM drugs.关键词
细胞自噬/缺血性脑卒中/文献计量学/Cite Space/VOS viewerKey words
cellular autophagy/ischemic stroke/bibliometrics/Cite Space/VOS viewer分类
医药卫生引用本文复制引用
陈笑一,龙佳欣,田梦芝,彭南波,杜可..细胞自噬在缺血性脑卒中作用的可视化分析[J].神经损伤与功能重建,2025,20(7):395-401,7.基金项目
湖南省自然科学基金项目(黄芪介导DJ-1/PTEN/mTOR通路双向调节神经元自噬抗脑缺血损伤机制研究,No.2020JJ9050) （黄芪介导DJ-1/PTEN/mTOR通路双向调节神经元自噬抗脑缺血损伤机制研究,No.2020JJ9050）
国家重点实验室开放基金(NMN介于DJ1调控PI3K/Akt/mTOR通路诱导线粒体自噬抗脑缺血损伤作用及机制研究,No.GTZK201711) （NMN介于DJ1调控PI3K/Akt/mTOR通路诱导线粒体自噬抗脑缺血损伤作用及机制研究,No.GTZK201711）
研究生创新创业训练计划项目(血筒素介导PTEN/mTOR/HIF-1α通路调控自噬抗缺血性卒中的机制研究,No.CX20230828) （血筒素介导PTEN/mTOR/HIF-1α通路调控自噬抗缺血性卒中的机制研究,No.CX20230828）
2022年度湖南省普通高等学校教学改革研究项目(《药理学》课程思政构建,培养同频共振专业人才及队伍,No.HNJG-2022-0134重点项) （《药理学》课程思政构建,培养同频共振专业人才及队伍,No.HNJG-2022-0134重点项）
