保健医学研究与实践2025，Vol.22Issue(4)：57-62,6.DOI:10.11986/j.issn.1673-873X.2025.04.09
倍他司汀+氟桂利嗪联合眩晕治疗仪治疗良性阵发性位置性眩晕的疗效观察
Efficacy observation of betahistine combined with flunarizine and vertigo therapeutic apparatus for benign paroxysmal positional vertigo
摘要
Abstract
Objective To investigate the efficacy of betahistine combined with flunarizine and vertigo therapeutic apparatus for benign paroxysmal positional vertigo(BPPV),providing references for clinical treatment.Methods A total of 106 BPPV pa-tients admitted to Fuyang Hospital Affiliated to Anhui Medical University from October 2021 to January 2024 were enrolled.Patients were assigned to two groups(n=53 each)using a random number table.The control group received betahistine com-bined with flunarizine.The study group received additional vertigo therapeutic apparatus.Dizziness Handicap Inventory(DHI)and Vertigo Symptom Scale(VSI)scores were compared before treatment and at 1 and 3 weeks of treatment.Clinical efficacy and prognosis were compared between groups.Results Before treatment,no significant difference was noted in DHI scores between groups(P>0.05);at 1 and 3 weeks of treatment,DHI scores decreased significantly in both groups compared to pre-treatment levels,with the study group significantly lower than the control group(P<0.05).Before treatment,no significant difference was observed in VSI scores between groups(P>0.05);at 1 and 3 weeks of treatment,VSI scores decreased signifi-cantly in both groups compared to pre-treatment levels,with the study group significantly lower than the control group(P<0.05).The overall response rate was significantly higher in the study group than in the control group(P<0.05).No signifi-cant difference was found in adverse reaction rates between groups(P>0.05).The recurrence rate was significantly lower in the study group than in the control group(P<0.05).Conclusion The combined approach(betahistine combined with flunari-zine and vertigo therapeutic apparatus)achieves precise repositioning through the apparatus while restoring inner ear balance function pharmacologically,demonstrating superior overall efficacy and prognosis.This provides a comprehensive and effective treatment regimen for BPPV patients.关键词
倍他司汀/氟桂利嗪/眩晕治疗仪/良性阵发性位置性眩晕/预后Key words
Betahistine/Flunarizine/Vertigo therapeutic apparatus/Benign paroxysmal positional vertigo/Prognosis分类
医药卫生引用本文复制引用
李波,童洋萍,云宗金,肖改荣,杨俊影,张群,宋斌..倍他司汀+氟桂利嗪联合眩晕治疗仪治疗良性阵发性位置性眩晕的疗效观察[J].保健医学研究与实践,2025,22(4):57-62,6.基金项目
湖南省卫生健康委2020年度科研立项课题(20201928). （20201928）
