广州医药2025，Vol.56Issue(6)：782-786,5.DOI:10.20223/j.cnki.1000-8535.2025.06.008
晚期早产儿中小于胎龄儿的铁代谢状态分析
Analysis of iron metabolism status of small for gestational age among late preterm infants
陈锦文 1王慧琴 1汪家安 1李小燕 1施昌宏2
作者信息
- 1. 合肥市妇幼保健院新生儿科(安徽 合肥 230001)
- 2. 广州医科大学公共卫生学院(广东 广州 511436)
- 折叠
摘要
Abstract
Objective To explore the iron metabolism status in late preterm infants who are small for gestational age(SGA)compared to those appropriate for gestational age(AGA)at birth.Methods A total of 150 late preterm infants(gestational age 34 to 36+6 weeks)admitted to the Maternal and Child Health Hospital of Hefei from January to December 2020 were selected as the study subjects.The preterm infants were divided into the SGA group(36 cases)and the AGA group(114 cases)according to birth weight and gestational age.The iron metabolism status at birth was analyzed and compared between the two groups of preterm infants,and multiple linear regression analysis was applied to identify the influencing factors of serum iron.Results Compared with the AGA group,SGA infants had lower serum iron(14.5[11.4,17.1]vs 16.4[14.1,18.4],P=0.004),lower serum iron protein(135.6[101.8,176.2]vs 172.5[123.0,218.3],P=0.009),and lower total iron binding capacity(30.4[26.8,34.9]vs 35.4[29.5,44.6]P=0.001).There were no statistically significant differences in hemoglobin,mean corpuscular volume,mean corpuscular hemoglobin,and mean corpuscular hemoglobin concentration between the two groups of preterm infants(P＞0.05).Among the perinatal characteristics of preterm infants,placental abnormalities(β=-1.949,P=0.009)and the occurrence of maternal diabetes(β=-2.324,P=0.001)were significantly negatively correlated with serum iron levels.Conclusions Compared with preterm infants appropriate for gestational age,preterm infants who are small for gestational age have lower iron reserves at birth.Adequate supplementation of iron has a promoting effect on the physical development of small for gestational age newborns.关键词
铁代谢/早产儿/小于胎龄儿Key words
iron metabolism/preterm infants/small for gestational age引用本文复制引用
陈锦文,王慧琴,汪家安,李小燕,施昌宏..晚期早产儿中小于胎龄儿的铁代谢状态分析[J].广州医药,2025,56(6):782-786,5.
