中医学报2025，Vol.40Issue(8)：1629-1633,5.DOI:10.16368/j.issn.1674-8999.2025.08.261
从肾论治慢性衰老之骨脑共病
Treatment of Bone and Brain Comorbidity with Chronic Aging from Perspective of Kidney
摘要
Abstract
The integrated concept of"Kidney-bone-marrow-brain"is a complete physiological and pathological understanding sys-tem based on the theory proposed in Huang Di Nei Jing,which takes the Kidney as the foundation,the Essence as the intermediate sub-stance,the Du meridian as the intermediate channel,and the bone and brain as the target organs.The Essence of the Five Zang and Six Fu stores in the Kidney.The Kidney nourishes bone and produces marrow.The medullary fluid has the function of"bone flexion and ex-tension,discharge the nutrition and nourish the cerebral medulla",and the medullary flow is injected into the bone to supplement the bone marrow,to nourish and strengthen the bone.The medulla is filled with the cerebral marrow to support man's quick thinking and wisdom.In the physiological state,the Kidney,bone and brain promote each other.Specifically,the Essence of the bone in the Kidney can be filled in the brain,and the cerebral marrow can also be sent to the Kidney and bone.These three complement each other.In the pathological state,the three are causal and interrelated,and the feedback is aggravated.Kidney deficiency and lack of medulla,difficulty in replenishing the bones and brains,which can lead to bone dryness and brain emptiness,which can be manifested as osteoporosis,stroke and other bone and brain diseases.Stroke and other brain diseases have insufficient cerebral spinal cord,and the medullary tract cannot be placed in the bone orifice,which can lead to bone drying,bone dystrophy,manifested as osteoporosis and other bone metabo-lism diseases.Therefore,"Kidney-bone-marrow-brain"is not only a physiological state,but also a pathological comorbidity linkage system.Kidney Qi deficiency and Kidney Essence deficiency are common pathogenesis,and the clinical syndrome is characterized by chronic prolongation and difficult to heal,and injuries include that on the body and in spirit.In terms of treatment,medicine belong to animal products and medicines with strong flavor and taste can be used to nourish the Kidney and marrow,to strengthen the brain and bone.Besides,Qi tonifying medicine can be used to strengthen the Middle Jiao of body,which means to nourish Kidney by tonifying Spleen and Stomach.关键词
慢性衰老/肾/骨/髓/脑/骨脑共病/从肾论治Key words
chronic aging/Kidney/bone/marrow/brain/bone and brain comorbidity/treatment from the perspective of Kidney分类
医药卫生引用本文复制引用
龚洲,李志更,岳利峰,马培,刘鑫雨,吴柔燕,贾岳津,胡天时,王明阳,刘金瑛,张靓..从肾论治慢性衰老之骨脑共病[J].中医学报,2025,40(8):1629-1633,5.基金项目
国家自然科学基金面上项目(82174046) （82174046）
中国医学科学院医学与健康科技创新工程项目(2022-I2M-2-002) （2022-I2M-2-002）
