华侨大学学报（自然科学版）2025，Vol.46Issue(4)：361-368,8.DOI:10.11830/ISSN.1000-5013.202503027
铁死亡在鼻咽癌发生发展及治疗中的研究进展
Research Progress of Ferroptosis in Pathogenesis and Therapy of Nasopharyngeal Carcinoma
摘要
Abstract
By reviewing the relevant literature in recent years,the concept,characteristics and research pro-gress of ferroptosis in the treatment of nasopharyngeal carcinoma were reviewed.The results showed that the mechanism of ferroptosis was complex and it played a key role in the treatment of nasopharyngeal carcinoma.Although the long-term survival rate of nasopharyngeal carcinoma patients had significantly increased,distant metastasis and resistance to radiotherapy and chemotherapy remained the treatment difficulties for nasopharyn-geal carcinoma patients.As a novel mode of cell death characterized by elevated levels of reactive oxygen spe-cies and lipid peroxides,ferroptosis was expected to become a new target for clinical intervention in nasopha-ryngeal carcinoma.关键词
鼻咽癌/铁死亡/发生机制/耐药性Key words
nasopharyngeal carcinoma/ferroptosis/mechanism/antibiotics resistance分类
医药卫生引用本文复制引用
王福财,周智涵,马丽浩..铁死亡在鼻咽癌发生发展及治疗中的研究进展[J].华侨大学学报（自然科学版）,2025,46(4):361-368,8.基金项目
国家自然科学基金资助项目(81860354) （81860354）
福建省泉州市高层次人才创新创业项目(2022C015R) （2022C015R）
