机器人外科学杂志（中英文）2025，Vol.6Issue(7)：1122-1127,6.DOI:10.12180/j.issn.2096-7721.2025.07.008
经脐三臂法机器人辅助根治性前列腺切除术治疗寡转移性前列腺癌的近期疗效
Short-term efficacy of transumbilical three-arm robot-assisted radical prostatectomy for oligometastatic prostate cancer
摘要
Abstract
Objective:To investigate the short-term clinical outcomes of transumbilical three-arm robot-assisted radical prostatectomy(TTRARP)for oligometastatic prostate cancer(omPCa).Methods:100 omPCa patients who were treated at Sichuan Provincial People's Hospital from January 2020 to May 2023 were selected and divided into the study group(n=51,receiving TTRARP surgery combined with drug treatment)and the control group(n=49,receiving drug treatment).Prostate-specific antigen(PSA)levels,complication rates,and castration-resistant prostate cancer-free survival(CRPC-free survival)were compared between the two groups of patients.Results:One month after intervention,there was no statistically significant difference in PSA levels between the two groups(P>0.05),but the average PSA decline rate was higher in the study group than that in the control group(P<0.05).One year after intervention,there was no statistically significant difference in PSA levels or the average decline rates between the two groups(P>0.05).The study group showed slower cumulative risk progression than the control group,and the overall survival rate was higher in the study group than that in the control group.Multivariate analysis identified prostatic capsular penetration,≥4 metastatic lesions,and Gleason score>8 as independent risk factors for shortened CRPC-free survival.Conclusion:TTRARP can effectively reduce PSA levels and prolong CRPC-free survival in the short term,especially for patients with<4 metastases,Gleason score≤8 and intact prostatic capsule,but the risk of anastomotic fistula should be concerned.关键词
机器人辅助手术/根治性前列腺切除术/寡转移性前列腺癌/临床效果Key words
Robot-assisted Surgery/Radical Prostatectomy/Oligometastatic Prostate Cancer/Clinical Outcome分类
医药卫生引用本文复制引用
刘畅林,刘伯萸,赵婷,张赢予..经脐三臂法机器人辅助根治性前列腺切除术治疗寡转移性前列腺癌的近期疗效[J].机器人外科学杂志（中英文）,2025,6(7):1122-1127,6.基金项目
2017年中国医药教育协会护理项目(药教协(项)字[2017]第001号)Nursing Program of Chinese Medicine Education Association in 2017(CMEA No.[2017]001) （药教协(项）
