实用临床医药杂志2025，Vol.29Issue(11)：7-13,7.DOI:10.7619/jcmp.20245435
不同人体测量指标评估慢性肾脏病患者体脂含量的价值
Values of varied anthropometric indicators in assessing body fat content in patients with chronic kidney disease
摘要
Abstract
Objective To evaluate the predictive value of different anthropometric indices in as-sessing body fat content in patients with chronic kidney disease(CKD).Methods Bioelectrical im-pedance analysis was used to measure body fat percentage and visceral fat area in 279 non-dialysis CKD patients.Height and body mass were measured to calculate body mass index(BMI).Waist and hip circumferences were measured to calculate waist-to-hip ratio.Skinfold thickness(triceps skinfold thickness and subscapular skinfold thickness)was also measured.Pearson correlation analysis was employed to explore the correlations between anthropometric indices and body fat percentage as well as visceral fat area.Receiver operating characteristic(ROC)curves were plotted,and the DeLong test was conducted to compare the differences in the area under the curve(AUC)of the ROC curves.Results Pearson correlation analysis revealed significant correlations between body fat percentage and BMI(r=0.419,P＜0.001),hip circumference(r=0.450,P＜0.001),triceps skinfold thickness(r=0.229,P＜0.001),and subscapular skinfold thickness(r=0.324,P＜0.001).Significant correlations were also observed between visceral fat area and BMI(r=0.658,P＜0.001),hip circumference(r=0.648,P＜0.001),triceps skinfold thickness(r=0.194,P=0.001),and subscapular skinfold thickness(r=0.333,P＜0.001).ROC curve analysis demonstrated that the triceps skinfold thickness had the largest AUC value(0.732)for diagnosing obesity in CKD patients,with a sensitivity of 62.1％and specificity of 78.8％,indicating a moderate diagnostic performance.BMI and hip circumference had AUC values of 0.806 and 0.804,respectively,for as-sessing visceral obesity in CKD patients,showing good diagnostic performance.In contrast,the waist-to-hip ratio exhibited poor diagnostic value for both overall obesity and visceral obesity.Conclusion Measuring BMI and hip circumference is valuable for diagnosing visceral fat accumula-tion in CKD patients.However,when assessing overall obesity in CKD patients,multiple anthropo-metric indices should be combined for comprehensive evaluation.Additionally,our results indicate that different anthropometric indices have varying diagnostic values for different types of obesity,ne-cessitating appropriate selection based on actual circumstances.关键词
慢性肾脏病/体脂百分比/内脏脂肪面积/人体测量指标/生物电阻抗/皮褶厚度/整体肥胖/内脏型肥胖Key words
chronic kidney disease/body fat percentage/visceral fat area/anthropometric indices/bioelectrical impedance/skinfold thickness/overall obesity/visceral obesity分类
医药卫生引用本文复制引用
姜洁,贾梦雪,毕光宇,徐道亮,刘文进..不同人体测量指标评估慢性肾脏病患者体脂含量的价值[J].实用临床医药杂志,2025,29(11):7-13,7.基金项目
国家自然科学基金青年基金项目(82302133) （82302133）
江苏省扬州市科技局社会发展项目(YZ2022094) （YZ2022094）
江苏省扬州市科技局市级重点实验室项目(YZ2022169) （YZ2022169）
